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1. Zinc cyanide

   Shi, Shicheng; Szostak, Michal (January 2018, Eros)

   First update on zinc cyanide for all chemists planning or working on organic syntheses is presented. 

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2. Zinc uptake in the Basidiomycota: Characterization of zinc transporters in Ustilago maydis

   https://doi.org/10.1080/09687688.2019.1667034  

   Martha-Paz, Adriana M.; Eide, David; Mendoza-Cózatl, David; Castro-Guerrero, Norma A.; Aréchiga-Carvajal, Elva T. (January 2019, Molecular Membrane Biology)
3. Catalytic Asymmetric Synthesis of Zinc Metallacycles

   https://doi.org/10.1021/jacs.3c05885  

   Bishop, Hayden D.; Zhao, Qiang; Uyeda, Christopher (September 2023, Journal of the American Chemical Society)

   Transition-metal-catalyzed reductive coupling reactions of alkynes and imines are attractive methods for the synthesis of chiral allylic amines. Mechanistically, these reactions involve an oxidative cyclization of the alkyne and the imine to generate a metallacyclic intermediate, which then reacts with H2 or an H2 surrogate to form the product. As an alternative to this hydrogenolysis pathway, here we show that transmetallation to zinc can occur, forming a zinc metallacycle product. This organozinc product serves as a versatile nucleophile for carbon–carbon and carbon–heteroatom coupling reactions. Mechanistic studies based on isotopic labelling experiments and DFT calculations suggest that the key transmetallation step occurs between a Co(II) species and ZnCl2. 

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4. Zinc Finger Readers of Methylated DNA

   https://doi.org/10.3390/molecules23102555  

   Hudson, Nicholas O.; Buck-Koehntop, Bethany A. (October 2018, Molecules)

   DNA methylation is a prevalent epigenetic modification involved in regulating a number of essential cellular processes, including genomic accessibility and transcriptional outcomes. As such, aberrant alterations in global DNA methylation patterns have been associated with a growing number of disease conditions. Nevertheless, the full mechanisms by which DNA methylation information is interpreted and translated into genomic responses is not yet fully understood. Methyl-CpG binding proteins (MBPs) function as important mediators of this essential process by selectively reading DNA methylation signals and translating this information into down-stream cellular outcomes. The Cys2His2 zinc finger scaffold is one of the most abundant DNA binding motifs found within human transcription factors, yet only a few zinc finger containing proteins capable of conferring selectivity for mCpG over CpG sites have been characterized. This review summarizes our current structural understanding for the mechanisms by which the zinc finger MBPs evaluated to date read this essential epigenetic mark. Further, some of the biological implications for mCpG readout elicited by this family of MBPs are discussed. 

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5. Synthesis of Zinc phthalocyanines within Zeolites

   Glass, A; Rana, G; Bakker, M G; Bindu, M M (October 2024, American Chemical Society)

   Efficient oxidation catalysts are critical for advancing technologies such as fuel cells and carbon dioxide reduction Transition metal phthalocyanines, such as zinc phthalocyanine (ZnPC) and zinc perfluorophthalocyanine (ZnF PC) , show promise due to their catalytic potential, despite challenges from aggregation-induced activity loss. This research focuses on synthe sizing ZnPC and ZnF PC within zeolite Na-X (FAU) to leverage the zeolite′s confined environment to prevent aggregation and enhance the catalytic performance. Exptl. methodologies encompass ion exchange and melt synthesis techniques to synthesize Zn PC and ZnF PC within the zeolite matrix. Initial results demonstrate successful synthesis of Zn PC and ZnF PC in/on zeolite CBV780, based on characterization by diffuse reflec tance UV-Vis spectroscopy. To confirm that the phthalocyanines are made within the zeolite rather than on the outside of the zeolite, extensive washing using Soxhlet extraction is used to remove all phthalocyanines formed on the exterior of the zeolite. There are four fluorines in each phthalonitrile mol., and four phthalonitriles make a phthalocyanine, hence there are 16 fluorine atoms in a phthaloc yanine; "hexadecyl fluorophthalocyanine" would be correct, but is a mouthfull; hence perfluor ophthalocyanine. 

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