skip to main content
US FlagAn official website of the United States government
dot gov icon
Official websites use .gov
A .gov website belongs to an official government organization in the United States.
https lock icon
Secure .gov websites use HTTPS
A lock ( lock ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.


Title: A Novel Plate-Like Sensor Utilizing Curvature-Based Stiffening for Nanometrology Applications
In this study, we propose a novel plate-like sensor which utilizes curvature-based stiffening effects for enhanced nanometrology. In the proposed concept, the stiffness and natural frequencies of the sensor can be arbitrarily adjusted by applying a transverse curvature via piezoelectric actuators, thereby enabling resonance amplification over a broad range of frequencies. The concept is validated using a macroscale experiment. Then, a microscale finite element analysis is used to study the effect of applied curvature on the microplate static stiffness and natural frequencies. We show that imposed transverse curvature is an effective way to tune the in-situ static stiffness and natural frequencies of the plate sensor system. These findings will form the basis of future curvature-based stiffening microscale studies for novel scenarios in atomic force microscopy.  more » « less
Award ID(s):
1847513 1660448
PAR ID:
10254026
Author(s) / Creator(s):
; ; ; ;
Date Published:
Journal Name:
ASME 2020 Dynamic Systems and Control Conference
Volume:
2
Page Range / eLocation ID:
V002T34A002
Format(s):
Medium: X
Sponsoring Org:
National Science Foundation
More Like this
  1. null (Ed.)
    Abstract Numerous nanometrology techniques concerned with probing a wide range of frequency-dependent properties would benefit from a cantilevered sensor with tunable natural frequencies. In this work, we propose a method to arbitrarily tune the stiffness and natural frequencies of a microplate sensor for atomic force microscope applications, thereby allowing resonance amplification at a broad range of frequencies. This method is predicated on the principle of curvature-based stiffening. A macroscale experiment is conducted to verify the feasibility of the method. Next, a microscale finite element analysis is conducted on a proof-of-concept device. We show that both the stiffness and various natural frequencies of the device can be controlled through applied transverse curvature. Dynamic phenomena encountered in the method, such as eigenvalue curve veering, are discussed and methods are presented to accommodate these phenomena. We believe that this study will facilitate the development of future curvature-based microscale sensors for atomic force microscopy applications. 
    more » « less
  2. In this paper two nonlinear effects are investigated. One is the effect of the static stiffness nonlinearity in changing the linear dynamic natural frequency and the other is the combination of nonlinear stiffness and nonlinear inertia effects in changing the nonlinear dynamic transient response due to a change in the initial release state of the system. A theoretical model has been developed for a cantilevered thin plate with a range of length to width ratio using beam theory and considering both stiffness and inertial nonlinearities in the model. Lagrange’s equation was used to deduce nonlinear inertia and stiffness matrices for a modal representation. Some insights into how these nonlinear components influence the beam response are presented. Measurements with both a hammer test and also a release test of cantilevered thin plates were done using different configurations and tip mass values. Results from static and dynamic analysis using the linear and the nonlinear theoretical model show good agreement between theory and experiment for natural frequencies and the amplitude displacements versus time. 
    more » « less
  3. Abstract Biological processes are inherently dynamic, necessitating biomaterial platforms capable of spatiotemporal control over cellular organization and matrix stiffness for accurate study of tissue development, wound healing, and disease. However, most in vitro platforms remain static. In this study, a dynamic biomaterial platform comprising a stiffening hydrogel is introduced and achieved through a stepwise approach of addition followed by light‐mediated crosslinking, integrated with an elastomeric substrate featuring strain‐responsive lamellar surface patterns. Employing this platform, the response of human induced pluripotent stem cell‐derived cardiomyocytes (hIPSC‐CMs) is investigated to dynamic stiffening from healthy to fibrotic tissue stiffness. The results demonstrate that culturing hIPSC‐CMs on physiologically relevant healthy stiffness significantly enhances their function, as evidenced by increased sarcomere fraction, wider sarcomere width, significantly higher connexin‐43 content, and elevated cell beating frequency compared to cells cultured on fibrotic matrix. Conversely, dynamic matrix stiffening negatively impacts hIPSC‐CM function, with earlier stiffening events exerting a more pronounced hindering effect. These findings provide valuable insights into material‐based approaches for addressing existing challenges in hIPSC‐CM maturation and have broader implications across various tissue models, including muscle, tendon, nerve, and cornea, where both cellular alignment and matrix stiffening play pivotal roles in tissue development and regeneration. 
    more » « less
  4. null (Ed.)
    Inflated continuum robots are promising for a variety of navigation tasks, but controlling their motion with a small number of actuators is challenging. These inflated beam robots tend to buckle under compressive loads, producing extremely tight local curvature at difficult-to-control buckle point locations. In this paper, we present an inflated beam robot that uses distributed stiffness changing sections enabled by positive pressure layer jamming to control or prevent buckling. Passive valves are actuated by an electromagnet carried by an electromechanical device that travels inside the main inflated beam robot body. The valves themselves require no external connections or wiring, allowing the distributed stiffness control to be scaled to long beam lengths. Multiple layer jamming elements are stiffened simultaneously to achieve global stiffening, allowing the robot to support greater cantilevered loads and longer unsupported lengths. Local stiffening, achieved by leaving certain layer jamming elements unstiffened, allows the robot to produce "virtual joints" that dynamically change the robot kinematics. Implementing these stiffening strategies is compatible with growth through tip eversion and tendon steering, and enables a number of new capabilities for inflated beam robots and tip-everting robots. 
    more » « less
  5. Lung diseases such as cancer substantially alter the mechanical properties of the organ with direct impact on the development, progression, diagnosis, and treatment response of diseases. Despite significant interest in the lung’s material properties, measuring the stiffness of intact lungs at sub-alveolar resolution has not been possible. Recently, we developed the crystal ribcage to image functioning lungs at optical resolution while controlling physiological parameters such as air pressure. Here, we introduce a data-driven, multiscale network model that takes images of the lung at different distending pressures, acquired via the crystal ribcage, and produces corresponding absolute stiffness maps. Following validation, we report absolute stiffness maps of the functioning lung at microscale resolution in health and disease. For representative images of a healthy lung and a lung with primary cancer, we find that while the lung exhibits significant stiffness heterogeneity at the microscale, primary tumors introduce even greater heterogeneity into the lung’s microenvironment. Additionally, we observe that while the healthy alveoli exhibit strain-stiffening of ∼1.75 times, the tumor’s stiffness increases by a factor of six across the range of measured transpulmonary pressures. While the tumor stiffness is 1.4 times the lung stiffness at a transpulmonary pressure of three cmH2O, the tumor’s mean stiffness is nearly five times greater than that of the surrounding tissue at a transpulmonary pressure of 18 cmH2O. Finally, we report that the variance in both strain and stiffness increases with transpulmonary pressure in both the healthy and cancerous lungs. Our new method allows quantitative assessment of disease-induced stiffness changes in the alveoli with implications for mechanotransduction. 
    more » « less