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1. Exploration of Solid Forms of Crisaborole: Crystal Engineering Identifies Polymorphism in Commercial Sources and Facilitates Cocrystal Formation

   https://doi.org/10.1021/acs.cgd.8b00375  

   Campillo-Alvarado, Gonzalo ; Didden, Tighe D. ; Oburn, Shalisa M. ; Swenson, Dale C. ; MacGillivray, Leonard R. ( June 2018 , Crystal Growth & Design)
2. Crystal structure and photoreactivity of a halogen-bonded cocrystal based upon 1,2-diiodoperchlorobenzene and 1,2-bis(pyridin-4-yl)ethylene

   https://doi.org/10.1107/S2053229620006233  

   Bosch, Eric ; Battle, Jessica D. ; Groeneman, Ryan H. ( June 2020 , Acta Crystallographica Section C Structural Chemistry)

   null (Ed.)

   The formation of a photoreactive cocrystal based upon 1,2-diiodoperchlorobenzene ( 1,2-C 6 I 2 Cl 4 ) and trans -1,2-bis(pyridin-4-yl)ethylene ( BPE ) has been achieved. The resulting cocrystal, 2( 1,2-C 6 I 2 Cl 4 )·( BPE ) or C 6 Cl 4 I 2 ·0.5C 12 H 10 N 2 , comprises planar sheets of the components held together by the combination of I...N halogen bonds and halogen–halogen contacts. Notably, the 1,2-C 6 I 2 Cl 4 molecules π-stack in a homogeneous and face-to-face orientation that results in an infinite column of the halogen-bond donor. As a consequence of this stacking arrangement and I...N halogen bonds, molecules of BPE also stack in this type of pattern. In particular, neighbouring ethylene groups in BPE are found to be parallel and within the accepted distance for a photoreaction. Upon exposure to ultraviolet light, the cocrystal undergoes a solid-state [2 + 2] cycloaddition reaction that produces rctt -tetrakis(pyridin-4-yl)cyclobutane ( TPCB ) with an overall yield of 89%. A solvent-free approach utilizing dry vortex grinding of the components also resulted in a photoreactive material with a similar yield. 

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3. Unusual single crystal to single crystal phase transition of a nicotine salt monitored using temperature dependent single crystal X-ray diffraction

   https://doi.org/10.1039/D3CE00042G  

   Angevine, Devin J. ; Mitchell, Travis ; Zhang, Xiaotong ; Benedict, Jason B. ( April 2023 , CrystEngComm)

   The organic salt ( S )-nicotinium 2,6-dihydroxybenzoate undergoes reversible single crystal to single crystal phase transition at 104 K. The phase transition was monitored using temperature dependent single crystal X-ray diffraction and was attributed to symmetry breaking translations and rotations of the crystal components. 

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4. Color-Tunable Upconversion-Emission Switch Based on Cocrystal-to-Cocrystal Transformation

   https://doi.org/10.1021/jacs.2c11425  

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5. Single-crystal-to-single-crystal guest exchange in columnar assembled brominated triphenylamine bis-urea macrocycles

   https://doi.org/10.1039/c9cc01725a  

   Sindt, Ammon J. ; Smith, Mark D. ; Berens, Samuel ; Vasenkov, Sergey ; Bowers, Clifford R. ; Shimizu, Linda S. ( May 2019 , Chemical Communications)

   Self-assembly of brominated triphenylamine bis-urea macrocycles affords robust porous materials. Urea hydrogen bonds organize these building blocks into 1-dimensional columns, which pack via halogen–aryl interactions. The crystals are stable when emptied, present two distinct absorption sites for Xe with restricted Xe diffusion, and exhibit single-crystal-to-single-crystal guest exchange. 

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