Abstract Background Mass spectrometry (MS) uses mass-to-charge ratios of measured particles to decode the identities and quantities of molecules in a sample. Interpretation of raw MS depends upon data processing algorithms that render it human-interpretable. Quantitative MS workflows are complex experimental chains and it is crucial to know the performance and bias of each data processing method as they impact accuracy, coverage, and statistical significance of the result. Creation of the ground truth necessary for quantitatively evaluating MS1-aware algorithms is difficult and tedious task, and better software for creating such datasets would facilitate more extensive evaluation and improvement of MS data processing algorithms. Results We present JS-MS 2.0, a software suite that provides a dependency-free, browser-based, one click, cross-platform solution for creating MS1 ground truth. The software retains the first version’s capacity for loading, viewing, and navigating MS1 data in 2- and 3-D, and adds tools for capturing, editing, saving, and viewing isotopic envelope and extracted isotopic chromatogram features. The software can also be used to view and explore the results of feature finding algorithms. Conclusions JS-MS 2.0 enables faster creation and inspection of MS1 ground truth data. It is publicly available with an MIT license at github.com/optimusmoose/jsms.
Evaluation of Headset-based Viewing and Desktop-based Viewing of Remote Lectures in a Social VR Platform
- Award ID(s):
- Publication Date:
- NSF-PAR ID:
- Journal Name:
- VRST '20: 26th ACM Symposium on Virtual Reality Software and Technology
- Sponsoring Org:
- National Science Foundation
More Like this
Texture-based features computed on eye movement scan paths have recently been proposed for eye movement biometric applications. Feature vectors were extracted within this prior work by computing the mean and standard deviation of the resulting images obtained through application of a Gabor filter bank. This paper describes preliminary work exploring an alternative technique for extracting features from Gabor filtered scan path images. Namely, features vectors are obtained by downsampling the filtered images, thereby retaining structured spatial information within the feature vector. The proposed technique is validated at various downsampling scales for data collected from 94 subjects during free-viewing of a fantasy movie trailer. The approach is demonstrated to reduce EER versus the previously proposed statistical summary technique by 11.7% for the best evaluated downsampling parameter.