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Title: Reference-agnostic representation and visualization of pan-genomes
Abstract BackgroundThe pan-genome of a species is the union of the genes and non-coding sequences present in all individuals (cultivar, accessions, or strains) within that species. ResultsHere we introduce PGV, a reference-agnostic representation of the pan-genome of a species based on the notion of consensus ordering. Our experimental results demonstrate that PGV enables an intuitive, effective and interactive visualization of a pan-genome by providing a genome browser that can elucidate complex structural genomic variations. ConclusionsThe PGV software can be installed via conda or downloaded fromhttps://github.com/ucrbioinfo/PGV. The companion PGV browser athttp://pgv.cs.ucr.educan be tested using example bed tracks available from the GitHub page.  more » « less
Award ID(s):
1814359
PAR ID:
10306443
Author(s) / Creator(s):
;
Publisher / Repository:
Springer Science + Business Media
Date Published:
Journal Name:
BMC Bioinformatics
Volume:
22
Issue:
1
ISSN:
1471-2105
Format(s):
Medium: X
Sponsoring Org:
National Science Foundation
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