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1. Design patterns for the industrial Internet of Things

   https://doi.org/10.1109/WFCS.2018.8402353  

   Bloom, Gedare ; Alsulami, Bassma ; Nwafor, Ebelechukwu ; Bertolotti, Ivan Cibrario ( June 2018 , 2018 14th IEEE International Workshop on Factory Communication Systems (WFCS))

   The Internet of Things (IoT) is a vast collection of interconnected sensors, devices, and services that share data and information over the Internet with the objective of leveraging multiple information sources to optimize related systems. The technologies associated with the IoT have significantly improved the quality of many existing applications by reducing costs, improving functionality, increasing access to resources, and enhancing automation. The adoption of IoT by industries has led to the next industrial revolution: Industry 4.0. The rise of the Industrial IoT (IIoT) promises to enhance factory management, process optimization, worker safety, and more. However, the rollout of the IIoT is not without significant issues, and many of these act as major barriers that prevent fully achieving the vision of Industry 4.0. One major area of concern is the security and privacy of the massive datasets that are captured and stored, which may leak information about intellectual property, trade secrets, and other competitive knowledge. As a way forward toward solving security and privacy concerns, we aim in this paper to identify common input-output (I/O) design patterns that exist in applications of the IIoT. These design patterns enable constructing an abstract model representation of data flow semantics used by suchmore »applications, and therefore better understand how to secure the information related to IIoT operations. In this paper, we describe communication protocols and identify common I/O design patterns for IIoT applications with an emphasis on data flow in edge devices, which, in the industrial control system (ICS) setting, are most often involved in process control or monitoring.« less
2. Automatically eliminating speculative leaks from cryptographic code with blade

   https://doi.org/10.1145/3434330  

   Vassena, Marco ; Disselkoen, Craig ; Gleissenthall, Klaus von ; Cauligi, Sunjay ; Kıcı, Rami Gökhan ; Jhala, Ranjit ; Tullsen, Dean ; Stefan, Deian ( January 2021 , Proceedings of the ACM on Programming Languages)

   We introduce Blade, a new approach to automatically and efficiently eliminate speculative leaks from cryptographic code. Blade is built on the insight that to stop leaks via speculative execution, it suffices to cut the dataflow from expressions that speculatively introduce secrets ( sources ) to those that leak them through the cache ( sinks ), rather than prohibit speculation altogether. We formalize this insight in a static type system that (1) types each expression as either transient , i.e., possibly containing speculative secrets or as being stable , and (2) prohibits speculative leaks by requiring that all sink expressions are stable. Blade relies on a new abstract primitive, protect , to halt speculation at fine granularity. We formalize and implement protect using existing architectural mechanisms, and show how Blade’s type system can automatically synthesize a minimal number of protect s to provably eliminate speculative leaks. We implement Blade in the Cranelift WebAssembly compiler and evaluate our approach by repairing several verified, yet vulnerable WebAssembly implementations of cryptographic primitives. We find that Blade can fix existing programs that leak via speculation automatically , without user intervention, and efficiently even when using fences to implement protect .
3. Convergent selection of a WD40 protein that enhances grain yield in maize and rice

   https://doi.org/10.1126/science.abg7985  

   Chen, Wenkang ; Chen, Lu ; Zhang, Xuan ; Yang, Ning ; Guo, Jianghua ; Wang, Min ; Ji, Shenghui ; Zhao, Xiangyu ; Yin, Pengfei ; Cai, Lichun ; et al ( March 2022 , Science)

   INTRODUCTION During the independent process of cereal evolution, many trait shifts appear to have been under convergent selection to meet the specific needs of humans. Identification of convergently selected genes across cereals could help to clarify the evolution of crop species and to accelerate breeding programs. In the past several decades, researchers have debated whether convergent phenotypic selection in distinct lineages is driven by conserved molecular changes or by diverse molecular pathways. Two of the most economically important crops, maize and rice, display some conserved phenotypic shifts—including loss of seed dispersal, decreased seed dormancy, and increased grain number during evolution—even though they experienced independent selection. Hence, maize and rice can serve as an excellent system for understanding the extent of convergent selection among cereals. RATIONALE Despite the identification of a few convergently selected genes, our understanding of the extent of molecular convergence on a genome-wide scale between maize and rice is very limited. To learn how often selection acts on orthologous genes, we investigated the functions and molecular evolution of the grain yield quantitative trait locus KRN2 in maize and its rice ortholog OsKRN2 . We also identified convergently selected genes on a genome-wide scale in maize and rice, usingmore »two large datasets. RESULTS We identified a selected gene, KRN2 ( kernel row number2 ), that differs between domesticated maize and its wild ancestor, teosinte. This gene underlies a major quantitative trait locus for kernel row number in maize. Selection in the noncoding upstream regions resulted in a reduction of KRN2 expression and an increased grain number through an increase in kernel rows. The rice ortholog, OsKRN2 , also underwent selection and negatively regulates grain number via control of secondary panicle branches. These orthologs encode WD40 proteins and function synergistically with a gene of unknown function, DUF1644, which suggests that a conserved protein interaction controls grain number in maize and rice. Field tests show that knockout of KRN2 in maize or OsKRN2 in rice increased grain yield by ~10% and ~8%, respectively, with no apparent trade-off in other agronomic traits. This suggests potential applications of KRN2 and its orthologs for crop improvement. On a genome-wide scale, we identified a set of 490 orthologous genes that underwent convergent selection during maize and rice evolution, including KRN2/OsKRN2 . We found that the convergently selected orthologous genes appear to be significantly enriched in two specific pathways in both maize and rice: starch and sucrose metabolism, and biosynthesis of cofactors. A deep analysis of convergently selected genes in the starch metabolic pathway indicates that the degree of genetic convergence via convergent selection is related to the conservation and complexity of the gene network for a given selection. CONCLUSION Our findings show that common phenotypic shifts during maize and rice evolution acting on conserved genes are driven at least in part by convergent selection, which in maize and rice likely occurred both during and after domestication. We provide evolutionary and functional evidence on the convergent selection of KRN2/OsKRN2 for grain number between maize and rice. We further found that a complete loss-of-function allele of KRN2/OsKRN2 increased grain yield without an apparent negative impact on other agronomic traits. Exploring the role of KRN2/OsKRN2 and other convergently selected genes across the cereals could provide new opportunities to enhance the production of other global crops. Shared selected orthologous genes in maize and rice for convergent phenotypic shifts during domestication and improvement. By comparing 3163 selected genes in maize and 18,755 selected genes in rice, we identified 490 orthologous gene pairs, including KRN2 and its rice ortholog OsKRN2 , as having been convergently selected. Knockout of KRN2 in maize or OsKRN2 in rice increased grain yield by increasing kernel rows and secondary panicle branches, respectively.« less
4. Flexible Program Alignment to Deliver Data-Driven Feedback to Novice Programmers

   https://doi.org/10.1007/978-3-030-80421-3_27  

   Marin, Victor J. ; Contractor, Maheen Riaz ; Rivero, Carlos R. ( July 2021 , Lecture notes in computer science)

   Cristea, Alexandra I. ; Troussas, Christos (Ed.)

   Supporting novice programming learners at scale has become a necessity. Such a support generally consists of delivering automated feedback on what and why learners did incorrectly. Existing approaches cast the problem as automatically repairing learners’ incorrect programs; specifically, data-driven approaches assume there exists a correct program provided by other learner that can be extrapolated to repair an incorrect program. Unfortunately, their repair potential, i.e., their capability of providing feedback, is hindered by how they compare programs. In this paper, we propose a flexible program alignment based on program dependence graphs, which we enrich with semantic information extracted from the programs, i.e., operations and calls. Having a correct and an incorrect graphs, we exploit approximate graph alignment to find correspondences at the statement level between them. Each correspondence has a similarity attached to it that reflects the matching affinity between two statements based on topology (control and data flow information) and semantics (operations and calls). Repair suggestions are discovered based on this similarity. We evaluate our flexible approach with respect to rigid schemes over correct and incorrect programs belonging to nine real-world introductory programming assignments. We show that our flexible program alignment is feasible in practice, achieves better performance than rigidmore »program comparisons, and is more resilient when limiting the number of available correct programs.« less
5. ACE-SNN: Algorithm-Hardware Co-design of Energy-Efficient & Low-Latency Deep Spiking Neural Networks for 3D Image Recognition

   https://doi.org/10.3389/fnins.2022.815258  

   Datta, Gourav ; Kundu, Souvik ; Jaiswal, Akhilesh R. ; Beerel, Peter A. ( April 2022 , Frontiers in Neuroscience)

   High-quality 3D image recognition is an important component of many vision and robotics systems. However, the accurate processing of these images requires the use of compute-expensive 3D Convolutional Neural Networks (CNNs). To address this challenge, we propose the use of Spiking Neural Networks (SNNs) that are generated from iso-architecture CNNs and trained with quantization-aware gradient descent to optimize their weights, membrane leak, and firing thresholds. During both training and inference, the analog pixel values of a 3D image are directly applied to the input layer of the SNN without the need to convert to a spike-train. This significantly reduces the training and inference latency and results in high degree of activation sparsity, which yields significant improvements in computational efficiency. However, this introduces energy-hungry digital multiplications in the first layer of our models, which we propose to mitigate using a processing-in-memory (PIM) architecture. To evaluate our proposal, we propose a 3D and a 3D/2D hybrid SNN-compatible convolutional architecture and choose hyperspectral imaging (HSI) as an application for 3D image recognition. We achieve overall test accuracy of 98.68, 99.50, and 97.95% with 5 time steps (inference latency) and 6-bit weight quantization on the Indian Pines, Pavia University, and Salinas Scene datasets, respectively.more »In particular, our models implemented using standard digital hardware achieved accuracies similar to state-of-the-art (SOTA) with ~560.6× and ~44.8× less average energy than an iso-architecture full-precision and 6-bit quantized CNN, respectively. Adopting the PIM architecture in the first layer, further improves the average energy, delay, and energy-delay-product (EDP) by 30, 7, and 38%, respectively.« less