skip to main content


Title: The International Virus Bioinformatics Meeting 2022
The International Virus Bioinformatics Meeting 2022 took place online, on 23–25 March 2022, and has attracted about 380 participants from all over the world. The goal of the meeting was to provide a meaningful and interactive scientific environment to promote discussion and collaboration and to inspire and suggest new research directions and questions. The participants created a highly interactive scientific environment even without physical face-to-face interactions. This meeting is a focal point to gain an insight into the state-of-the-art of the virus bioinformatics research landscape and to interact with researchers in the forefront as well as aspiring young scientists. The meeting featured eight invited and 18 contributed talks in eight sessions on three days, as well as 52 posters, which were presented during three virtual poster sessions. The main topics were: SARS-CoV-2, viral emergence and surveillance, virus–host interactions, viral sequence analysis, virus identification and annotation, phages, and viral diversity. This report summarizes the main research findings and highlights presented at the meeting.  more » « less
Award ID(s):
1951678
NSF-PAR ID:
10327854
Author(s) / Creator(s):
; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; more » ; ; ; ; ; ; « less
Date Published:
Journal Name:
Viruses
Volume:
14
Issue:
5
ISSN:
1999-4915
Page Range / eLocation ID:
973
Format(s):
Medium: X
Sponsoring Org:
National Science Foundation
More Like this
  1. This report is a summary of the mini-conference on Workforce Development Through Research-Based, Plasma-Focused Science Education and Public Engagement held during the 2022 American Physical Society Division of Plasma Physics annual meeting. The motivation for organizing this mini-conference originates from recent studies and community-based reports highlighting important issues with the current state of the plasma workforce. Here, we summarize the main findings presented in the two speaker sessions of the mini-conference, the challenges, and recommendations identified in the discussion sessions and the results from a post-conference survey. We further provide information on initiatives and studies presented at the mini-conference, along with references to further resources. 
    more » « less
  2. The 5th International Workshop on Software Engineering Education for the Next Generation was held on May 16, 2023 in Melbourne, Australia. The workshop was part of the 45th International Conference on Software Engineering. It specifically supported the general theme of Educating the Next Generation of Software Engineers. Building on its predecessors, the workshop used a highly interactive format, structured around eight short paper presentations to generate discussion topics, an activity to select the most interesting topics, and structured breakout sessions. This enabled the participants to discuss the most interesting topics in detail. Participants presented the results of the breakout sessions using mind maps. 
    more » « less
  3. To provide early career scientists with professional development related to science communication, we developed a full day workshop funded by the National Science Foundation (NSF) entitledDeveloping the Science of Science Communication. This workshop has been funded since 2019 by NSF and presented in both virtual and in‐person formats. Because of the success of the virtual 2021 workshop and building upon foundations from prior years (in‐person in February 2019 and February 2020), a second virtual workshop was held in conjunction with the Ocean Sciences Meeting in January 2022. 2022 workshop attendees voluntarily participated in a full day virtual workshop comprised of verbal and visual communication skill sessions. In previous years, attendance was capped at 50 participants. In 2022, only 17 participants completed the pre‐workshop survey. The all‐day workshop included two presentation skills‐focused sessions and two poster design sessions. Participants overwhelmingly agreed that they (a) would recommend the workshop to others and (b) found the workshop content would be useful in their careers. The low attendance in 2022 is believed to be due to the virtual format combined with the timing of the workshop. In years prior, the workshop was held the day before the conference. This year, we attempted to hold the workshop 1 month prior to the conference to help students prepare in advance—we think most students simply had not prepared their presentations this far in advance. NSF has already funded an exciting future workshop structure for 2023. The workshop will be held across 2 days with a virtual “pre‐workshop” day for those who are ready and would like extra time and materials along with a second, in‐person workshop the day prior to the conference in Palma de Mallorca, Spain in conjunction with the June 2023 Aquatic Sciences Meeting.

     
    more » « less
  4. Frappier, Lori (Ed.)
    ABSTRACT Two new structures of the N-terminal domain of the main replication protein, NS1, of human parvovirus B19 (B19V) are presented here. This domain (NS1-nuc) plays an important role in the “rolling hairpin” replication of the single-stranded B19V DNA genome, recognizing origin of replication sequences in double-stranded DNA, and cleaving (i.e., nicking) single-stranded DNA at a nearby site known as the terminal resolution site (trs). The three-dimensional structure of NS1-nuc is well conserved between the two forms, as well as with a previously solved structure of a sequence variant of the same domain; however, it is shown here at a significantly higher resolution (2.4 Å). Using structures of NS1-nuc homologues bound to single- and double-stranded DNA, models for DNA recognition and nicking by B19V NS1-nuc are presented that predict residues important for DNA cleavage and for sequence-specific recognition at the viral origin of replication. IMPORTANCE The high-resolution structure of the DNA binding and cleavage domain of the main replicative protein, NS1, from the human-pathogenic virus human parvovirus B19 is presented here. Included also are predictions of how the protein recognizes important sequences in the viral DNA which are required for viral replication. These predictions can be used to further investigate the function of this protein, as well as to predict the effects on viral viability due to mutations in the viral protein and viral DNA sequences. Finally, the high-resolution structure facilitates structure-guided drug design efforts to develop antiviral compounds against this important human pathogen. 
    more » « less
  5. The CSSI 2019 workshop was held on October 28-29, 2019, in Austin, Texas. The main objectives of this workshop were to (1) understand the impact of the CSSI program on the community over the last 9 years, (2) engage workshop participants in identifying gaps and opportunities in the current CSSI landscape, (3) gather ideas on the cyberinfrastructure needs and expectations of the community with respect to the CSSI program, and (4) prepare a report summarizing the feedback gathered from the community that can inform the future solicitations of the CSSI program. The workshop participants included a diverse mix of researchers and practitioners from academia, industry, and national laboratories. The participants belonged to diverse domains such as quantum physics, computational biology, High Performance Computing (HPC), and library science. Almost 50% participants were from computer science domain and roughly 50% were from non-computer science domains. As per the self-reported statistics, roughly 27% of the participants were from the different underrepresented groups as defined by the National Science Foundation (NSF). The workshop brought together different stakeholders interested in provisioning sustainable cyberinfrastructure that can power discoveries impacting the various fields of science and technology and maintaining the nation's competitiveness in the areas such as scientific software, HPC, networking, cybersecurity, and data/information science. The workshop served as a venue for gathering the community-feedback on the current state of the CSSI program and its future directions. Before they arrived at the workshop, the participants were encouraged to take an online survey on the challenges that they face in using the current cyberinfrastructure and the importance of the CSSI program in enabling cutting-edge research. The workshop included 16 brain-storming sessions of one hour each. Additionally, the workshop program included 16 lightning talks and an extempore session. The information collected from the survey, brainstorming sessions, lightning talks, and the extempore session are summarized in this report and can potentially be useful for the NSF in formulating the future CSSI solicitations. The workshop fostered an environment in which the participants were encouraged to identify gaps and opportunities in the current cyberinfrastructure landscape, and develop thoughts for proposing new projects. 
    more » « less