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Title: Marine Microbial Siderophores: Reactivity and Structural Diversity
Most bacteria require iron to grow, yet soluble forms of iron are largely not available to microbes due to a combination of low solubility of ferric ion in the environment and sequestration in proteins and enzymes in living organisms. Microbes therefore compete for iron in various ways, including by production of siderophores, which are ligands with a high affinity for ferric ion and which facilitate transport of Fe(III) into and within bacteria. This review summarizes our work on the classes of siderophores isolated from open ocean isolates, including suites of amphiphilic siderophores that vary in the nature of the fatty acid appendages, photoreactive Fe(III)-siderophore complexes as a result of coordination to -hydroxy carboxylic acid groups, and a new series of tris catechol siderophores.  more » « less
Award ID(s):
2108596
PAR ID:
10359606
Author(s) / Creator(s):
Publisher / Repository:
American Institute of Chemists
Date Published:
Journal Name:
The chemist
ISSN:
1945-0702
Format(s):
Medium: X
Sponsoring Org:
National Science Foundation
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