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  • Organocatalytic synthesis of β-enaminyl radicals as the single-electron donors for phenyliodine(III) dicarboxylates: Direct one-pot alkylation-aminoxidation of styrenes
Title: Organocatalytic synthesis of β-enaminyl radicals as the single-electron donors for phenyliodine(III) dicarboxylates: Direct one-pot alkylation-aminoxidation of styrenes
A direct one-pot alkylation-aminoxidation of styrene derivatives was achieved by using in-situ-generated alkyl and N-oxyl radicals. The corresponding O-alkylated hydroxylamine derivatives were obtained in moderate to good yields. The reaction features the generation of the alkyl radicals from phenyliodine(III) dicarboxylates via an organocatalytic process, the use of phenyliodine(III) dicarboxylates as the source of the alkyl radicals and the oxidant for the generation of the N-oxyl radicals, and the first generation of the β-enaminyl radicals via a HAT process and their use as the single-electron donors.  more » « less
Award ID(s):
1664278
PAR ID:
10386929
Author(s) / Creator(s):
; ; ;
Date Published:
Journal Name:
Organic & Biomolecular Chemistry
ISSN:
1477-0520
Format(s):
Medium: X
Sponsoring Org:
National Science Foundation
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