More Like this

1. FaaSNet: Scalable and Fast Provisioning of Custom Serverless Container Runtimes at Alibaba Cloud Function Compute

   Wang, Ao ; Chang, Shuai ; Tian, Huangshi ; Wang, Hongqi ; Yang, Haoran ; Li, Huiba ; Du, Rui ; Cheng, Yue. ( July 2021 , 2021 USENIX Annual Technical Conference (USENIX ATC 21))

   Serverless computing, or Function-as-a-Service (FaaS), enables a new way of building and scaling applications by allowing users to deploy fine-grained functions while providing fully-managed resource provisioning and auto-scaling. Custom FaaS container support is gaining traction as it enables better control over OSes, versioning, and tooling for modernizing FaaS applications. However, providing rapid container provisioning introduces non-trivial challenges for FaaS providers, since container provisioning is costly, and real-world FaaS workloads exhibit highly dynamic patterns. In this paper, we design FaaSNet, a highly-scalable middleware system for accelerating FaaS container provisioning. FaaSNet is driven by the workload and infrastructure requirements of the FaaS platform at one of the world's largest cloud providers, Alibaba Cloud Function Compute. FaaSNet enables scalable container provisioning via a lightweight, adaptive function tree (FT) structure. FaaSNet uses an I/O efficient, on-demand fetching mechanism to further reduce provisioning costs at scale. We implement and integrate FaaSNet in Alibaba Cloud Function Compute. Evaluation results show that FaaSNet: (1) finishes provisioning 2,500 function containers on 1,000 virtual machines in 8.3 seconds, (2) scales 13.4× and 16.3× faster than Alibaba Cloud's current FaaS platform and a state-of-the-art P2P container registry (Kraken), respectively, and (3) sustains a bursty workload using 75.2% less time than an optimized baseline. 

   more » « less
2. The Temple University Digital Pathology Corpus: The Breast Tissue Subset

   https://doi.org/10.1109/SPMB52430.2021.9672275  

   Wevodau, Z. ; Doshna, B. ; Jhala, N. ; Akhtar, I. ; Obeid, I. ; Picone, J. ( December 2021 , Proceedings of the IEEE Signal Processing in Medicine and Biology Symposium (SPMB))

   Obeid, I. (Ed.)

   The Neural Engineering Data Consortium (NEDC) is developing the Temple University Digital Pathology Corpus (TUDP), an open source database of high-resolution images from scanned pathology samples [1], as part of its National Science Foundation-funded Major Research Instrumentation grant titled “MRI: High Performance Digital Pathology Using Big Data and Machine Learning” [2]. The long-term goal of this project is to release one million images. We have currently scanned over 100,000 images and are in the process of annotating breast tissue data for our first official corpus release, v1.0.0. This release contains 3,505 annotated images of breast tissue including 74 patients with cancerous diagnoses (out of a total of 296 patients). In this poster, we will present an analysis of this corpus and discuss the challenges we have faced in efficiently producing high quality annotations of breast tissue. It is well known that state of the art algorithms in machine learning require vast amounts of data. Fields such as speech recognition [3], image recognition [4] and text processing [5] are able to deliver impressive performance with complex deep learning models because they have developed large corpora to support training of extremely high-dimensional models (e.g., billions of parameters). Other fields that do not have access to such data resources must rely on techniques in which existing models can be adapted to new datasets [6]. A preliminary version of this breast corpus release was tested in a pilot study using a baseline machine learning system, ResNet18 [7], that leverages several open-source Python tools. The pilot corpus was divided into three sets: train, development, and evaluation. Portions of these slides were manually annotated [1] using the nine labels in Table 1 [8] to identify five to ten examples of pathological features on each slide. Not every pathological feature is annotated, meaning excluded areas can include focuses particular to these labels that are not used for training. A summary of the number of patches within each label is given in Table 2. To maintain a balanced training set, 1,000 patches of each label were used to train the machine learning model. Throughout all sets, only annotated patches were involved in model development. The performance of this model in identifying all the patches in the evaluation set can be seen in the confusion matrix of classification accuracy in Table 3. The highest performing labels were background, 97% correct identification, and artifact, 76% correct identification. A correlation exists between labels with more than 6,000 development patches and accurate performance on the evaluation set. Additionally, these results indicated a need to further refine the annotation of invasive ductal carcinoma (“indc”), inflammation (“infl”), nonneoplastic features (“nneo”), normal (“norm”) and suspicious (“susp”). This pilot experiment motivated changes to the corpus that will be discussed in detail in this poster presentation. To increase the accuracy of the machine learning model, we modified how we addressed underperforming labels. One common source of error arose with how non-background labels were converted into patches. Large areas of background within other labels were isolated within a patch resulting in connective tissue misrepresenting a non-background label. In response, the annotation overlay margins were revised to exclude benign connective tissue in non-background labels. Corresponding patient reports and supporting immunohistochemical stains further guided annotation reviews. The microscopic diagnoses given by the primary pathologist in these reports detail the pathological findings within each tissue site, but not within each specific slide. The microscopic diagnoses informed revisions specifically targeting annotated regions classified as cancerous, ensuring that the labels “indc” and “dcis” were used only in situations where a micropathologist diagnosed it as such. Further differentiation of cancerous and precancerous labels, as well as the location of their focus on a slide, could be accomplished with supplemental immunohistochemically (IHC) stained slides. When distinguishing whether a focus is a nonneoplastic feature versus a cancerous growth, pathologists employ antigen targeting stains to the tissue in question to confirm the diagnosis. For example, a nonneoplastic feature of usual ductal hyperplasia will display diffuse staining for cytokeratin 5 (CK5) and no diffuse staining for estrogen receptor (ER), while a cancerous growth of ductal carcinoma in situ will have negative or focally positive staining for CK5 and diffuse staining for ER [9]. Many tissue samples contain cancerous and non-cancerous features with morphological overlaps that cause variability between annotators. The informative fields IHC slides provide could play an integral role in machine model pathology diagnostics. Following the revisions made on all the annotations, a second experiment was run using ResNet18. Compared to the pilot study, an increase of model prediction accuracy was seen for the labels indc, infl, nneo, norm, and null. This increase is correlated with an increase in annotated area and annotation accuracy. Model performance in identifying the suspicious label decreased by 25% due to the decrease of 57% in the total annotated area described by this label. A summary of the model performance is given in Table 4, which shows the new prediction accuracy and the absolute change in error rate compared to Table 3. The breast tissue subset we are developing includes 3,505 annotated breast pathology slides from 296 patients. The average size of a scanned SVS file is 363 MB. The annotations are stored in an XML format. A CSV version of the annotation file is also available which provides a flat, or simple, annotation that is easy for machine learning researchers to access and interface to their systems. Each patient is identified by an anonymized medical reference number. Within each patient’s directory, one or more sessions are identified, also anonymized to the first of the month in which the sample was taken. These sessions are broken into groupings of tissue taken on that date (in this case, breast tissue). A deidentified patient report stored as a flat text file is also available. Within these slides there are a total of 16,971 total annotated regions with an average of 4.84 annotations per slide. Among those annotations, 8,035 are non-cancerous (normal, background, null, and artifact,) 6,222 are carcinogenic signs (inflammation, nonneoplastic and suspicious,) and 2,714 are cancerous labels (ductal carcinoma in situ and invasive ductal carcinoma in situ.) The individual patients are split up into three sets: train, development, and evaluation. Of the 74 cancerous patients, 20 were allotted for both the development and evaluation sets, while the remain 34 were allotted for train. The remaining 222 patients were split up to preserve the overall distribution of labels within the corpus. This was done in hope of creating control sets for comparable studies. Overall, the development and evaluation sets each have 80 patients, while the training set has 136 patients. In a related component of this project, slides from the Fox Chase Cancer Center (FCCC) Biosample Repository (https://www.foxchase.org/research/facilities/genetic-research-facilities/biosample-repository -facility) are being digitized in addition to slides provided by Temple University Hospital. This data includes 18 different types of tissue including approximately 38.5% urinary tissue and 16.5% gynecological tissue. These slides and the metadata provided with them are already anonymized and include diagnoses in a spreadsheet with sample and patient ID. We plan to release over 13,000 unannotated slides from the FCCC Corpus simultaneously with v1.0.0 of TUDP. Details of this release will also be discussed in this poster. Few digitally annotated databases of pathology samples like TUDP exist due to the extensive data collection and processing required. The breast corpus subset should be released by November 2021. By December 2021 we should also release the unannotated FCCC data. We are currently annotating urinary tract data as well. We expect to release about 5,600 processed TUH slides in this subset. We have an additional 53,000 unprocessed TUH slides digitized. Corpora of this size will stimulate the development of a new generation of deep learning technology. In clinical settings where resources are limited, an assistive diagnoses model could support pathologists’ workload and even help prioritize suspected cancerous cases. ACKNOWLEDGMENTS This material is supported by the National Science Foundation under grants nos. CNS-1726188 and 1925494. Any opinions, findings, and conclusions or recommendations expressed in this material are those of the author(s) and do not necessarily reflect the views of the National Science Foundation. REFERENCES [1] N. Shawki et al., “The Temple University Digital Pathology Corpus,” in Signal Processing in Medicine and Biology: Emerging Trends in Research and Applications, 1st ed., I. Obeid, I. Selesnick, and J. Picone, Eds. New York City, New York, USA: Springer, 2020, pp. 67 104. https://www.springer.com/gp/book/9783030368432. [2] J. Picone, T. Farkas, I. Obeid, and Y. Persidsky, “MRI: High Performance Digital Pathology Using Big Data and Machine Learning.” Major Research Instrumentation (MRI), Division of Computer and Network Systems, Award No. 1726188, January 1, 2018 – December 31, 2021. https://www. isip.piconepress.com/projects/nsf_dpath/. [3] A. Gulati et al., “Conformer: Convolution-augmented Transformer for Speech Recognition,” in Proceedings of the Annual Conference of the International Speech Communication Association (INTERSPEECH), 2020, pp. 5036-5040. https://doi.org/10.21437/interspeech.2020-3015. [4] C.-J. Wu et al., “Machine Learning at Facebook: Understanding Inference at the Edge,” in Proceedings of the IEEE International Symposium on High Performance Computer Architecture (HPCA), 2019, pp. 331–344. https://ieeexplore.ieee.org/document/8675201. [5] I. Caswell and B. Liang, “Recent Advances in Google Translate,” Google AI Blog: The latest from Google Research, 2020. [Online]. Available: https://ai.googleblog.com/2020/06/recent-advances-in-google-translate.html. [Accessed: 01-Aug-2021]. [6] V. Khalkhali, N. Shawki, V. Shah, M. Golmohammadi, I. Obeid, and J. Picone, “Low Latency Real-Time Seizure Detection Using Transfer Deep Learning,” in Proceedings of the IEEE Signal Processing in Medicine and Biology Symposium (SPMB), 2021, pp. 1 7. https://www.isip. piconepress.com/publications/conference_proceedings/2021/ieee_spmb/eeg_transfer_learning/. [7] J. Picone, T. Farkas, I. Obeid, and Y. Persidsky, “MRI: High Performance Digital Pathology Using Big Data and Machine Learning,” Philadelphia, Pennsylvania, USA, 2020. https://www.isip.piconepress.com/publications/reports/2020/nsf/mri_dpath/. [8] I. Hunt, S. Husain, J. Simons, I. Obeid, and J. Picone, “Recent Advances in the Temple University Digital Pathology Corpus,” in Proceedings of the IEEE Signal Processing in Medicine and Biology Symposium (SPMB), 2019, pp. 1–4. https://ieeexplore.ieee.org/document/9037859. [9] A. P. Martinez, C. Cohen, K. Z. Hanley, and X. (Bill) Li, “Estrogen Receptor and Cytokeratin 5 Are Reliable Markers to Separate Usual Ductal Hyperplasia From Atypical Ductal Hyperplasia and Low-Grade Ductal Carcinoma In Situ,” Arch. Pathol. Lab. Med., vol. 140, no. 7, pp. 686–689, Apr. 2016. https://doi.org/10.5858/arpa.2015-0238-OA. 

   more » « less
3. Phase-Aware CPU Workload Forecasting

   Alcorta, Erika S. ; Rama, Pranav ; Aswin, Ramachandran ; Gerstlauer, Andreas ( January 2021 , International Conference on Embedded Computer Systems: Architectures, Modeling and Simulation (SAMOS))

   null (Ed.)

   Predicting workload behavior during execution is essential for dynamic resource optimization of processor systems. Early studies used simple prediction algorithms such as a history tables. More recently, researchers have applied advanced machine learning regression techniques. Workload prediction can be cast as a time series forecasting problem. Time series forecasting is an active research area with recent advances that have not been studied in the context of workload prediction. In this paper, we first perform a comparative study of representative time series forecasting techniques to predict the dynamic workload of applications running on a CPU. We adapt state-of-the-art matrix profile and dynamic linear models (DLMs) not previously applied to workload prediction and compare them against traditional SVM and LSTM models that have been popular for handling non-stationary data. We find that all time series forecasting models struggle to predict abrupt workload changes. These changes occur because workloads go through phases, where prior work has studied workload phase detection, classification and prediction. We propose a novel approach that combines time series forecasting with phase prediction. We process each phase as a separate time series and train one forecasting model per phase. At runtime, forecasts from phase-specific models are selected and combined based on the predicted phase behavior. We apply our approach to forecasting of SPEC workloads running on a state-of-the-art Intel machine. Our results show that an LSTM-based phase-aware predictor can forecast workload CPI with less than 8% mean absolute error while reducing CPI error by more than 12% on average compared to a non-phase-aware approach. 

   more » « less
4. MArk: Exploiting Cloud Services for Cost-Effective, SLO-Aware Machine Learning Inference Serving

   Zhang, Chengliang ; Yu, Minchen ; Wang, Wei ; Yan, Feng ( May 2019 , Proceedings of the USENIX Conference)

   The advances of Machine Learning (ML) have sparked a growing demand of ML-as-a-Service: developers train ML models and publish them in the cloud as online services to provide low-latency inference at scale. The key challenge of ML model serving is to meet the response-time Service-Level Objectives (SLOs) of inference workloads while minimizing the serving cost. In this paper, we tackle the dual challenge of SLO compliance and cost effectiveness with MArk (Model Ark), a general-purpose inference serving system built in Amazon Web Services (AWS). MArk employs three design choices tailor-made for inference workload. First, MArk dynamically batches requests and opportunistically serves them using expensive hardware accelerators (e.g., GPU) for improved performance-cost ratio. Second, instead of relying on feedback control scaling or over-provisioning to serve dynamic workload, which can be too slow or too expensive for inference serving, MArk employs predictive autoscaling to hide the provisioning latency at low cost. Third, given the stateless nature of inference serving, MArk exploits the flexible, yet costly serverless instances to cover the occasional load spikes that are hard to predict. We evaluated the performance of MArk using several state-of-the-art ML models trained in popular frameworks including TensorFlow, MXNet, and Keras. Compared with the premier industrial ML serving platform SageMaker, MArk reduces the serving cost up to 7.8× while achieving even better latency performance. 

   more » « less
5. Optimizing inference serving on serverless platforms

   https://doi.org/10.14778/3547305.3547313  

   Ali, Ahsan ; Pinciroli, Riccardo ; Yan, Feng ; Smirni, Evgenia ( June 2022 , Proceedings of the VLDB Endowment)

   Serverless computing is gaining popularity for machine learning (ML) serving workload due to its autonomous resource scaling, easy to use and pay-per-use cost model. Existing serverless platforms work well for image-based ML inference, where requests are homogeneous in service demands. That said, recent advances in natural language processing could not fully benefit from existing serverless platforms as their requests are intrinsically heterogeneous. Batching requests for processing can significantly increase ML serving efficiency while reducing monetary cost, thanks to the pay-per-use pricing model adopted by serverless platforms. Yet, batching heterogeneous ML requests leads to additional computation overhead as small requests need to be "padded" to the same size as large requests within the same batch. Reaching effective batching decisions (i.e., which requests should be batched together and why) is non-trivial: the padding overhead coupled with the serverless auto-scaling forms a complex optimization problem. To address this, we develop Multi-Buffer Serving (MBS), a framework that optimizes the batching of heterogeneous ML inference serving requests to minimize their monetary cost while meeting their service level objectives (SLOs). The core of MBS is a performance and cost estimator driven by analytical models supercharged by a Bayesian optimizer. MBS is prototyped and evaluated on AWS using bursty workloads. Experimental results show that MBS preserves SLOs while outperforming the state-of-the-art by up to 8 x in terms of cost savings while minimizing the padding overhead by up to 37 x with 3 x less number of serverless function invocations. 

   more » « less