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Title: The Origins and the Current Applications of Microfluidics-Based Magnetic Cell Separation Technologies
The magnetic separation of cells based on certain traits has a wide range of applications in microbiology, immunology, oncology, and hematology. Compared to bulk separation, performing magnetophoresis at micro scale presents advantages such as precise control of the environment, larger magnetic gradients in miniaturized dimensions, operational simplicity, system portability, high-throughput analysis, and lower costs. Since the first integration of magnetophoresis and microfluidics, many different approaches have been proposed to magnetically separate cells from suspensions at the micro scale. This review paper aims to provide an overview of the origins of microfluidic devices for magnetic cell separation and the recent technologies and applications grouped by the targeted cell types. For each application, exemplary experimental methods and results are discussed.  more » « less
Award ID(s):
1752170
PAR ID:
10407968
Author(s) / Creator(s):
; ;
Date Published:
Journal Name:
Magnetochemistry
Volume:
8
Issue:
1
ISSN:
2312-7481
Page Range / eLocation ID:
10
Format(s):
Medium: X
Sponsoring Org:
National Science Foundation
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