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Title: BENDing with Polycomb in pluripotency and cancer
Abstract

Three recent publications on BEND3 firmly establish its role as a novel sequence‐specific transcription factor that is essential for PRC2 recruitment and maintenance of pluripotency. Here, we briefly review our current understanding of the BEND3‐PRC2 axis in the regulation of pluripotency and also explore the possibility of a similar connection in cancer.

 
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Award ID(s):
1818286 2225464
NSF-PAR ID:
10414155
Author(s) / Creator(s):
 ;  
Publisher / Repository:
Wiley Blackwell (John Wiley & Sons)
Date Published:
Journal Name:
BioEssays
Volume:
45
Issue:
8
ISSN:
0265-9247
Format(s):
Medium: X
Sponsoring Org:
National Science Foundation
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