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Title: Peptide-based assembled nanostructures that can direct cellular responses
Abstract Natural originated materials have been well-studied over the past several decades owing to their higher biocompatibility compared to the traditional polymers. Peptides, consisting of amino acids, are among the most popular programmable building blocks, which is becoming a growing interest in nanobiotechnology. Structures assembled using those biomimetic peptides allow the exploration of chemical sequences beyond those been routinely used in biology. In this review, we discussed the most recent experimental discoveries on the peptide-based assembled nanostructures and their potential application at the cellular level such as drug delivery. In particular, we explored the fundamental principles of peptide self-assembly and the most recent development in improving their interactions with biological systems. We believe that as the fundamental knowledge of the peptide assemblies evolves, the more sophisticated and versatile nanostructures can be built, with promising biomedical applications.  more » « less
Award ID(s):
2023668
NSF-PAR ID:
10432146
Author(s) / Creator(s):
;
Date Published:
Journal Name:
Biomedical Materials
Volume:
17
Issue:
6
ISSN:
1748-6041
Page Range / eLocation ID:
062002
Format(s):
Medium: X
Sponsoring Org:
National Science Foundation
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