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Title: The Diversity and Functions of Plant RNA Modifications: What We Know and Where We Go from Here
Since the discovery of the first ribonucleic acid (RNA) modifications in transfer RNAs (tRNAs) and ribosomal RNAs (rRNAs), scientists have been on a quest to decipher the identities and functions of RNA modifications in biological systems. The last decade has seen monumental growth in the number of studies that have characterized and assessed the functionalities of RNA modifications in the field of plant biology. Owing to these studies, we now categorize RNA modifications based on their chemical nature and the RNA on which they are found, as well as the array of proteins that are involved in the processes that add, read, and remove them from an RNA molecule. Beyond their identity, another key piece of the puzzle is the functional significance of the various types of RNA modifications. Here, we shed light on recent studies that help establish our current understanding of the diversity of RNA modifications found in plant transcriptomes and the functions they play at both the molecular (e.g., RNA stability, translation, and transport) and organismal (e.g., stress response and development) levels. Finally, we consider the key research questions related to plant gene expression and biology in general and highlight developments in various technologies that are driving our insights forward in this research area.  more » « less
Award ID(s):
1849708
PAR ID:
10434643
Author(s) / Creator(s):
; ; ;
Date Published:
Journal Name:
Annual Review of Plant Biology
Volume:
74
Issue:
1
ISSN:
1543-5008
Page Range / eLocation ID:
53 to 85
Format(s):
Medium: X
Sponsoring Org:
National Science Foundation
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