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1. Specific and intraspecific diversity of Staphylinidae in southern High Appalachia

   Caterino, M.S. (October 2021, Entomological Society of America)
2. High-throughput and high-dimensional single-cell analysis of antigen-specific CD8+ T cells

   https://doi.org/10.1038/s41590-021-01073-2  

   Ma, Ke-Yue; Schonnesen, Alexandra A.; He, Chenfeng; Xia, Amanda Y.; Sun, Eric; Chen, Eunise; Sebastian, Katherine R.; Guo, Yu-Wan; Balderas, Robert; Kulkarni-Date, Mrinalini; et al (December 2021, Nature Immunology)
3. High-Performance Domain-Specific Library for Hydrologic Data Processing

   Kalyan Bhetwal (April 2023, ProQuest dissertations theses global)

   Cathie Olschanowsky (Ed.)

   Hydrologists must process many gigabytes of data for hydrologic simulations, which takes time and resources degrading performance. The performance issues are caused mainly by domain scientists’ preference for using Python, which trades performance for productivity. In my thesis, I demonstrate that using the static compilation technique to compile Python to generate C code along with several optimizations reduces time and resources for hydrologic data processing. I developed a Domain Specific Library (DSL) which is a subset of Python and compiles to Sparse Polyhedral Framework - Intermediate Representation (SPF-IR), which allows opportunities for optimizations like read reduction fusion which are not available in Python. We fused the file I/O to perform computation on small chunks of data (stream computation) in order to reduce the memory footprint. The C code we generated from SPF-IR shows an average speed-up of 2.58x over the existing hand-optimized implementations and can totally eliminate the tempo- rary storage required. DSL users can still enjoy the ease of use of Python but get performance better than the C code. 

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4. Engineering of high specific strength and low thermal conductivity cementitious composites with hollow glass microspheres for high-temperature high-pressure applications

   https://doi.org/https://doi.org/10.1016/j.cemconcomp.2020.103514  

   Krakowiak, K. J. (April 2020, Cement concrete composites)

   Lightweight cement-based composites with high specific strength and low thermal conductivity are highly sought in the energy and construction industries. These characteristics are important in designing cement liners for high-temperature, high-pressure (HTHP) wells, in addition to those operating in permafrost. Similar attributes are also desirable in designing cementitious composites for energy efficient building envelopes. This work reports the results of an experimental campaign focused on engineering lightweight cementitious composites with hollow glass microspheres. It is demonstrated that the chemical stability of microspheres at HTHP conditions can be directly controlled by modulating the specific surface area and dissolution rate constant of supplementary siliceous additives. In addition to the stabilizing effect, such additives lead to the pore structure refinement and the enhancement of interfacial transition zone (ITZ). Introduced lightweight composites are capable of delivering significant load bearing capacity when normally cured, which is greatly increased by hydrothermal curing. Such high specific strength composites possess thermal conductivity below 0.3 W/mK at the oven dry density <1000 kg/m3 and cement dosage <400 kg/m3. This class of cementitious composites bears potential to enhance zonal insulation and well integrity, as well as increasing energy efficiency of building envelopes. 

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5. Biomanufacturing of organ-specific tissues with high cellular density and embedded vascular channels

   https://doi.org/10.1126/sciadv.aaw2459  

   Skylar-Scott, Mark A.; Uzel, Sebastien G.; Nam, Lucy L.; Ahrens, John H.; Truby, Ryan L.; Damaraju, Sarita; Lewis, Jennifer A. (September 2019, Science Advances)

   Engineering organ-specific tissues for therapeutic applications is a grand challenge, requiring the fabrication and maintenance of densely cellular constructs composed of ~10 8 cells/ml. Organ building blocks (OBBs) composed of patient-specific–induced pluripotent stem cell–derived organoids offer a pathway to achieving tissues with the requisite cellular density, microarchitecture, and function. However, to date, scant attention has been devoted to their assembly into 3D tissue constructs. Here, we report a biomanufacturing method for assembling hundreds of thousands of these OBBs into living matrices with high cellular density into which perfusable vascular channels are introduced via embedded three-dimensional bioprinting. The OBB matrices exhibit the desired self-healing, viscoplastic behavior required for sacrificial writing into functional tissue (SWIFT). As an exemplar, we created a perfusable cardiac tissue that fuses and beats synchronously over a 7-day period. Our SWIFT biomanufacturing method enables the rapid assembly of perfusable patient- and organ-specific tissues at therapeutic scales. 

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