Metal-Mediated, Autolytic Amide Bond Cleavage: A Strategy for the Selective, Metal Complexation-Catalyzed, Controlled Release of Metallodrugs
- PAR ID:
- 10470464
- Publisher / Repository:
- American Chemical Society Publishing
- Date Published:
- Journal Name:
- Journal of the American Chemical Society
- Volume:
- 145
- Issue:
- 29
- ISSN:
- 0002-7863
- Page Range / eLocation ID:
- 16261 to 16270
- Format(s):
- Medium: X
- Sponsoring Org:
- National Science Foundation
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Abstract Metal–organic frameworks (MOFs) are crystalline, 2‐ and 3‐dimensional coordination polymers formed by bonding interactions between metals and multitopic organic ligands. These are typically formed using hard Lewis basic organic ligands with high oxidation state metal ions. The use of low‐valent metals as structural elements in MOFs is far less common, despite the widespread use of such metals for catalysis, luminescence, and other applications. This Minireview focuses on recent advances in the field of low‐valent MOFs and offers a perspective on the future development of these materials.more » « less
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