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Title: Improvements in Efficiency and Selectivity for C–F Bond Halogen-Exchange Reactions by Using Boron Reagents
Abstract The use of boron Lewis acids as instigators of bond cleavage offers a number of synthetic possibilities. A unique feature of this class of reagents is the ability to functionalize otherwise inert C–F bonds. We summarize notable developments in C–F bond halogen exchange using Lewis acidic boron reagents and we conclude by featuring our group’s advances in activating CF3 groups by using boron trihalides. 1 Introduction 2 Boron-Mediated Halogen Exchange 3 Mono-Selective C–F Activation 4 Conclusions  more » « less
Award ID(s):
2017828
PAR ID:
10480894
Author(s) / Creator(s):
; ;
Publisher / Repository:
Thieme
Date Published:
Journal Name:
Synlett
Volume:
34
Issue:
03
ISSN:
0936-5214
Page Range / eLocation ID:
193 to 202
Format(s):
Medium: X
Sponsoring Org:
National Science Foundation
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