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1. Direct Zinc Finger Protein Persulfidation by H 2 S Is Facilitated by Zn 2+

   https://doi.org/10.1002/ange.201900823  

   Lange, Mike ; Ok, Kiwon ; Shimberg, Geoffrey D. ; Bursac, Biljana ; Markó, Lajos ; Ivanović‐Burmazović, Ivana ; Michel, Sarah L. J. ; Filipovic, Milos R. ( May 2019 , Angewandte Chemie)

   H₂S is a gaseous signaling molecule that modifies cysteine residues in proteins to form persulfides (P‐SSH). One family of proteins modified by H₂S are zinc finger (ZF) proteins, which contain multiple zinc‐coordinating cysteine residues. Herein, we report the reactivity of H₂S with a ZF protein called tristetraprolin (TTP). Rapid persulfidation leading to complete thiol oxidation of TTP mediated by H₂S was observed by low‐temperature ESI‐MS and fluorescence spectroscopy. Persulfidation of TTP required O₂ , which reacts with H₂S to form superoxide, as detected by ESI‐MS, a hydroethidine fluorescence assay, and EPR spin trapping. H₂S was observed to inhibit TTP function (binding to TNFα mRNA) by an in vitro fluorescence anisotropy assay and to modulate TNFα in vivo. H₂S was unreactive towards TTP when the protein was bound to RNA, thus suggesting a protective effect of RNA.

    

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2. Direct Zinc Finger Protein Persulfidation by H 2 S Is Facilitated by Zn 2+

   https://doi.org/10.1002/anie.201900823  

   Lange, Mike ; Ok, Kiwon ; Shimberg, Geoffrey D. ; Bursac, Biljana ; Markó, Lajos ; Ivanović‐Burmazović, Ivana ; Michel, Sarah L. J. ; Filipovic, Milos R. ( May 2019 , Angewandte Chemie International Edition)

   H₂S is a gaseous signaling molecule that modifies cysteine residues in proteins to form persulfides (P‐SSH). One family of proteins modified by H₂S are zinc finger (ZF) proteins, which contain multiple zinc‐coordinating cysteine residues. Herein, we report the reactivity of H₂S with a ZF protein called tristetraprolin (TTP). Rapid persulfidation leading to complete thiol oxidation of TTP mediated by H₂S was observed by low‐temperature ESI‐MS and fluorescence spectroscopy. Persulfidation of TTP required O₂ , which reacts with H₂S to form superoxide, as detected by ESI‐MS, a hydroethidine fluorescence assay, and EPR spin trapping. H₂S was observed to inhibit TTP function (binding to TNFα mRNA) by an in vitro fluorescence anisotropy assay and to modulate TNFα in vivo. H₂S was unreactive towards TTP when the protein was bound to RNA, thus suggesting a protective effect of RNA.

    

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3. Superionic Conduction in K 3 SbS 4 Enabled by Cl‐Modified Anion Lattice

   https://doi.org/10.1002/ange.202408574  

   Chen, Yudan ; Wang, Pengbo ; Truong, Erica ; Ogbolu, Bright ; Jin, Yongkang ; Oyekunle, Ifeoluwa ; Liu, Haoyu ; Islam, M_Mahinur ; Poudel, Tej ; Huang, Chen ; et al ( July 2024 , Angewandte Chemie)

   All‐solid‐state potassium batteries emerge as promising alternatives to lithium batteries, leveraging their high natural abundance and cost‐effectiveness. Developing potassium solid electrolytes (SEs) with high room‐temperature ionic conductivity is critical for realizing efficient potassium batteries. In this study, we present the synthesis of K_2.98Sb_0.91S_3.53Cl_0.47, showcasing a room‐temperature ionic conductivity of 0.32 mS/cm and a low activation energy of 0.26 eV. This represents an increase of over two orders of magnitude compared to the parent compound K₃SbS₄, marking the highest reported ionic conductivity for non‐oxide potassium SEs. Solid‐state³⁹K magic‐angle‐spinning nuclear magnetic resonance on K_2.98Sb_0.91S_3.53Cl_0.47reveals an increased population of mobile K⁺ions with fast dynamics. Ab initio molecular dynamics (AIMD) simulations further confirm a delocalized K⁺density and significantly enhanced K⁺diffusion. This work demonstrates diversification of the anion sublattice as an effective approach to enhance ion transport and highlights K_2.98Sb_0.91S_3.53Cl_0.47as a promising SE for all‐solid‐state potassium batteries.

    

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4. Structural evolution during solution-based synthesis of Li 7 P 3 S 11 solid electrolyte by synchrotron X-ray total scattering

   https://doi.org/10.1039/D3TA02326E  

   Shao, Bowen ; Das, Ratnottam ; Huang, Yonglin ; Deng, Ruihao ; Seelman, Sara ; Han, Fudong ( August 2023 , Journal of Materials Chemistry A)

   Synchrotron X-ray total scattering and pair distribution function analysis are used to investigate the structural changes during solution synthesis of the Li₇P₃S₁₁solid electrolyte.

    

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5. Dramatically Enhanced Valley‐Polarized Emission by Alloying and Electrical Tuning of Monolayer WTe 2 x S 2(1‐ x ) Alloys at Room Temperature with 1T′‐WTe 2 ‐Contact

   https://doi.org/10.1002/advs.202304890  

   Lin, Wei‐Hsiang ; Li, Chia‐Shuo ; Wu, Chih‐I ; Rossman, George R. ; Atwater, Harry A. ; Yeh, Nai‐Chang ( November 2023 , Advanced Science)

   Monolayer ternary tellurides based on alloying different transition metal dichalcogenides (TMDs) can result in new two‐dimensional (2D) materials ranging from semiconductors to metals and superconductors with tunable optical and electrical properties. Semiconducting WTe_2xS_2(1‐x)monolayer possesses two inequivalent valleys in the Brillouin zone, each valley coupling selectively with circularly polarized light (CPL). The degree of valley polarization (DVP) under the excitation of CPL represents the purity of valley polarized photoluminescence (PL), a critical parameter for opto‐valleytronic applications. Here, new strategies to efficiently tailor the valley‐polarized PL from semiconducting monolayer WTe_2xS_2(1‐x)at room temperature (RT) through alloying and back‐gating are presented. The DVP at RT is found to increase drastically from < 5% in WS₂to 40% in WTe_0.12S_1.88by Te‐alloying to enhance the spin‐orbit coupling. Further enhancement and control of the DVP from 40% up to 75% is demonstrated by electrostatically doping the monolayer WTe_0.12S_1.88via metallic 1T′‐WTe₂electrodes, where the use of 1T′‐WTe₂substantially lowers the Schottky barrier height (SBH) and weakens the Fermi‐level pinning of the electrical contacts. The demonstration of drastically enhanced DVP and electrical tunability in the valley‐polarized emission from 1T′‐WTe₂/WTe_0.12S_1.88heterostructures paves new pathways towards harnessing valley excitons in ultrathin valleytronic devices for RT applications.

    

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