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Title: Alternating field electrospinning of blended fish gelatin/poly(ε-caprolactone) nanofibers
Blended nanofibrous biomaterials from natural and synthetic sources show promise for better biointegration. This study explores high-yield alternating field electrospinning (AFES) of blended cold-water fish skin gelatin (FGEL) and polycaprolactone (PCL) nanofibrous meshes with up to 30 wt% PCL at 7.8–14.4 g/h fiber productivity, depending on the composition. FGEL/PCL nanofibers reveal smooth surface morphology and 237–313 nm average diameters after thermal crosslinking. FTIR analysis indicated little FGEL/PCL interaction and notable changes in PCL crystallinity in the crosslinked nanofibers. A 14-days in-vitro analysis shows good cellular viability and nanofibrous FGEL/PCL mesh stability. Results demonstrate that AFES provides efficient, scalable production of blended FGEL/PCL nanofibrous biomaterials with suitable characteristics.  more » « less
Award ID(s):
1852207
PAR ID:
10489732
Author(s) / Creator(s):
; ; ;
Publisher / Repository:
Elsevier
Date Published:
Journal Name:
Materials Letters
Volume:
341
Issue:
C
ISSN:
0167-577X
Page Range / eLocation ID:
134284
Format(s):
Medium: X
Sponsoring Org:
National Science Foundation
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