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1. Thiol–Anhydride Dynamic Reversible Networks

   https://doi.org/10.1002/anie.202001388  

   Podgórski, Maciej; Mavila, Sudheendran; Huang, Sijia; Spurgin, Nathan; Sinha, Jasmine; Bowman, Christopher N. (June 2020, Angewandte Chemie International Edition)
2. Post-polymerization modification of styrene–maleic anhydride copolymer brushes

   https://doi.org/10.1039/c7py01659j  

   Guo, Wei; Xiong, Li; Reese, Cassandra M.; Amato, Douglas V.; Thompson, Brittany J.; Logan, Phillip K.; Patton, Derek L. (January 2017, Polymer Chemistry)

   Post-polymerization modification (PPM) has been broadly employed to achieve functional polymer brush surfaces via immobilization of functional moieties on the brush using efficient organic tranformations. Here, we demonstrate the amine-anhydride reaction as a modular PPM route to functional brush surfaces using poly(styrene–maleic anhydride) (pSMA) copolymer brushes as a platform. The amine-anhydride reaction on pSMA surfaces proceeds to high conversions, with rapid kinetics, under ambient reaction conditions, and exploits a readily available library of functional amines. Using cystamine as a modifier, a convenient route to thiol-functionalized brushes was developed that enables sequential PPM modifications with a large library of alkenes using both base-catalyzed thiol-Michael and radical-mediated thiol–ene reactions. The high fidelity PPM reactions were demonstrated via the development of multifunctional, micropatterned brush surfaces. 

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3. Micromolding of Amphotericin-B-Loaded Methoxyethylene–Maleic Anhydride Copolymer Microneedles

   https://doi.org/10.3390/pharmaceutics14081551  

   Azizi Machekposhti, Sina; Nguyen, Alexander K.; Vanderwal, Lyndsi; Stafslien, Shane; Narayan, Roger J. (August 2022, Pharmaceutics)

   Biocompatible and biodegradable materials have been used for fabricating polymeric microneedles to deliver therapeutic drug molecules through the skin. Microneedles have advantages over other drug delivery methods, such as low manufacturing cost, controlled drug release, and the reduction or absence of pain. The study examined the delivery of amphotericin B, an antifungal agent, using microneedles that were fabricated using a micromolding technique. The microneedle matrix was made from GantrezTM AN-119 BF, a benzene-free methyl vinyl ether/maleic anhydride copolymer. The GantrezTM AN-119 BF was mixed with water; after water evaporation, the polymer exhibited sufficient strength for microneedle fabrication. Molds cured at room temperature remained sharp and straight. SEM images showed straight and sharp needle tips; a confocal microscope was used to determine the height and tip diameter for the microneedles. Nanoindentation was used to obtain the hardness and Young’s modulus values of the polymer. Load–displacement testing was used to assess the failure force of the needles under compressive loading. These two mechanical tests confirmed the mechanical properties of the needles. In vitro studies validated the presence of amphotericin B in the needles and the antifungal properties of the needles. Amphotericin B GantrezTM microneedles fabricated in this study showed appropriate characteristics for clinical translation in terms of mechanical properties, sharpness, and antifungal properties. 

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4. Hydrogel Microcapsules with Dynamic pH-Responsive Properties from Methacrylic Anhydride

   https://doi.org/10.1021/acs.macromol.8b00843  

   Werner, Jörg G.; Nawar, Saraf; Solovev, Alexander A.; Weitz, David A. (July 2018, Macromolecules)
5. Acetic Acid Adsorption and Reactions on Pt and Ni

   Lotanna Ezeonu, Jason P. (June 2022, North American Catalysis Society Meeting (NAM-27) Conference in New York, NY in 2022)

   Lotanna Ezeonu, Jason P. Robbins, Ziyu Tang, Xiaofang Yang, Bruce E. Koel, Simon G. Podkolzin, "Acetic Acid Adsorption and Reactions on Pt and Ni", North American Catalysis Society Meeting (NAM-27) Conference in New York, NY in 2022, Presentation number Wed-P-88, https://nam.confex.com/nam/2022/meetingapp.cgi/Paper/28396 

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