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Title: Physical Forces in Regeneration of Cells and Tissues
The ability to regenerate after the loss of a part is a hallmark of living systems and occurs at both the tissue and organ scales, but also within individual cells. Regeneration entails many processes that are physical and mechanical in nature, including the closure of wounds, the repositioning of material from one place to another, and the restoration of symmetry following perturbations. However, we currently know far more about the genetics and molecular signaling pathways involved in regeneration, and there is a need to investigate the role of physical forces in the process. Here, we will provide an overview of how physical forces may play a role in wound healing and regeneration, in which we compare and contrast regenerative processes at the tissue and cell scales.  more » « less
Award ID(s):
2317444
PAR ID:
10525283
Author(s) / Creator(s):
;
Publisher / Repository:
Cold Spring Harbor Press
Date Published:
Journal Name:
Cold Spring Harbor Perspectives in Biology
ISSN:
1943-0264
Page Range / eLocation ID:
a041527
Format(s):
Medium: X
Sponsoring Org:
National Science Foundation
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