The conversion of lignocellulose‐rich biomass to bio‐based chemicals and higher order fuels remains a grand challenge, as single‐microbe approaches often cannot drive both deconstruction and chemical production steps. In contrast, consortia based bioprocessing leverages the strengths of different microbes to distribute metabolic loads and achieve process synergy, product diversity, and bolster yields. Here, we describe a biphasic fermentation scheme that combines the lignocellulolytic action of anaerobic fungi isolated from large herbivores with domesticated microbes for bioproduction. When grown in batch culture, anaerobic fungi release excess sugars from both cellulose and crude biomass due to a wealth of highly expressed carbohydrate active enzymes (CAZymes), converting as much as 49% of cellulose to free glucose. This sugar‐rich hydrolysate readily supports growth of
This content will become publicly available on June 1, 2025
- Award ID(s):
- 2128271
- NSF-PAR ID:
- 10532495
- Editor(s):
- na
- Publisher / Repository:
- Elsevier
- Date Published:
- Journal Name:
- Fungal Genetics and Biology
- Volume:
- 172
- Issue:
- C
- ISSN:
- 1087-1845
- Page Range / eLocation ID:
- 103897
- Format(s):
- Medium: X
- Sponsoring Org:
- National Science Foundation
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