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Better understanding of the dose-toxicity relationship is critical for safe dose escalation to improve local control in late-stage cervical cancer radiotherapy. In this study, we introduced a convolutional neural network (CNN) model to analyze rectum dose distribution and predict rectum toxicity. Forty-two cervical cancer patients treated with combined external beam radiotherapy (EBRT) and brachytherapy (BT) were retrospectively collected, including twelve toxicity patients and thirty non-toxicity patients. We adopted a transfer learning strategy to overcome the limited patient data issue. A 16-layers CNN developed by the visual geometry group (VGG-16) of the University of Oxford was pre-trained on a large-scale natural image database, ImageNet, and fine-tuned with patient rectum surface dose maps (RSDMs), which were accumulated EBRT + BT doses on the unfolded rectum surface. We used the adaptive synthetic sampling approach and the data augmentation method to address the two challenges, data imbalance and data scarcity. The gradient-weighted class activation maps (Grad-CAM) were also generated to highlight the discriminative regions on the RSDM along with the prediction model. We compare different CNN coefficients fine-tuning strategies, and compare the predictive performance using the traditional dose volume parameters, e.g. D 0.1/1/2cc, and the texture features extracted from the RSDM. Satisfactory prediction performance was achieved with the proposed scheme, and we found that the mean Grad-CAM over the toxicity patient group has geometric consistence of distribution with the statistical analysis result, which indicates possible rectum toxicity location. The evaluation results have demonstrated the feasibility of building a CNN-based rectum dose-toxicity prediction model with transfer learning for cervical cancer radiotherapy.
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Igniting Precision: Amplifying Wildfire Prediction in Diverse Regions via Teacher-Student Model Fusion
Accurate wildfire prediction in diverse and geographically dispersed areas is crucial for effective wildfire management. However, the limited availability of labeled data in data-challenged regions, along with the unique characteristics of these areas, poses challenges for training robust prediction models. This study investigates the performance of a convolutional neural network (CNN) on datasets comprising Landsat images from Canada and Alaska. Through principal component analysis (PCA), the study uncovers distinct differences in data distribution between the two regions. It is observed that the reduced data size of the Alaskan dataset, along with its distinct data distribution, leads to a decrease in the CNN's accuracy to 75% compared to an impressive 98% achieved on the Canadian dataset. To address this limitation, we propose a teacher-student model approach, transferring knowledge from a CNN trained on the larger Canadian dataset. The results demonstrate a significant accuracy improvement to 88.96% on the Alaskan dataset. Our findings highlight the effectiveness of the teacherstudent model in mitigating data scarcity challenges, enhancing wildfire prediction capabilities in regions with limited training data. This research contributes to improved wildfire monitoring and prevention strategies in challenging geographical locations.
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- PAR ID:
- 10537939
- Publisher / Repository:
- IEEE
- Date Published:
- ISBN:
- 979-8-3503-4534-6
- Page Range / eLocation ID:
- 528 to 535
- Format(s):
- Medium: X
- Location:
- Jacksonville, FL, USA
- Sponsoring Org:
- National Science Foundation
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- Free Publicly Accessible Full Text
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Accepted Manuscript1.0
- Conference Paper:
- https://doi.org/10.1109/ICMLA58977.2023.00079
