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Title: Artificial intelligence augmented home sleep apnea testing device study (AISAP study)
Study objectiveThis study aimed to prospectively validate the performance of an artificially augmented home sleep apnea testing device (WVU-device) and its patented technology. MethodologyThe WVU-device, utilizing patent pending (US 20210001122A) technology and an algorithm derived from cardio-pulmonary physiological parameters, comorbidities, and anthropological information was prospectively compared with a commercially available and Center for Medicare and Medicaid Services (CMS) approved home sleep apnea testing (HSAT) device. The WVU-device and the HSAT device were applied on separate hands of the patient during a single night study. The oxygen desaturation index (ODI) obtained from the WVU-device was compared to the respiratory event index (REI) derived from the HSAT device. ResultsA total of 78 consecutive patients were included in the prospective study. Of the 78 patients, 38 (48%) were women and 9 (12%) had a Fitzpatrick score of 3 or higher. The ODI obtained from the WVU-device corelated well with the HSAT device, and no significant bias was observed in the Bland-Altman curve. The accuracy for ODI > = 5 and REI > = 5 was 87%, for ODI> = 15 and REI > = 15 was 89% and for ODI> = 30 and REI of > = 30 was 95%. The sensitivity and specificity for these ODI /REI cut-offs were 0.92 and 0.78, 0.91 and 0.86, and 0.94 and 0.95, respectively. ConclusionThe WVU-device demonstrated good accuracy in predicting REI when compared to an approved HSAT device, even in patients with darker skin tones.  more » « less
Award ID(s):
2125872
PAR ID:
10538722
Author(s) / Creator(s):
; ; ; ; ;
Editor(s):
Grewal, Harpreet Singh
Publisher / Repository:
PLOS
Date Published:
Journal Name:
PLOS ONE
Volume:
19
Issue:
5
ISSN:
1932-6203
Page Range / eLocation ID:
e0303076
Format(s):
Medium: X
Sponsoring Org:
National Science Foundation
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