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ABSTRACT The current generation of galaxy simulations can resolve individual giant molecular clouds, the progenitors of dense star clusters. But the evolutionary fate of these young massive clusters, and whether they can become the old globular clusters (GCs) observed in many galaxies, is determined by a complex interplay of internal dynamical processes and external galactic effects. We present the first star-by-star N-body models of massive (N ∼ 105–107) star clusters formed in a FIRE-2 MHD simulation of a Milky Way-mass galaxy, with the relevant initial conditions and tidal forces extracted from the cosmological simulation. We select 895 (∼30 per cent) of the YMCs with >6 × 104 M⊙ from Grudić et al. 2022 and integrate them to z = 0 using the cluster Monte Carlo code, CMC. This procedure predicts a MW-like system with 148 GCs, predominantly formed during the early, bursty mode of star formation. Our GCs are younger, less massive, and more core-collapsed than clusters in the Milky Way or M31. This results from the assembly history and age-metallicity relationship of the host galaxy: Younger clusters are preferentially born in stronger tidal fields and initially retain fewer stellar-mass black holes, causing them to lose mass faster and reach core collapse sooner than older GCs. Our results suggest that the masses and core/half-light radii of GCs are shaped not only by internal dynamical processes, but also by the specific evolutionary history of their host galaxies. These results emphasize that N-body studies with realistic stellar physics are crucial to understanding the evolution and present-day properties of GC systems.
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This content will become publicly available on December 1, 2025
Biomolecular condensates form spatially inhomogeneous network fluids
The functions of biomolecular condensates are thought to be influenced by their material properties, and these will be determined by the internal organization of molecules within condensates. However, structural characterizations of condensates are challenging, and rarely reported. Here, we deploy a combination of small angle neutron scattering, fluorescence recovery after photobleaching, and coarse-grained molecular dynamics simulations to provide structural descriptions of model condensates that are formed by macromolecules from nucleolar granular components (GCs). We show that these minimal facsimiles of GCs form condensates that are network fluids featuring spatial inhomogeneities across different length scales that reflect the contributions of distinct protein and peptide domains. The network-like inhomogeneous organization is characterized by a coexistence of liquid- and gas-like macromolecular densities that engenders bimodality of internal molecular dynamics. These insights suggest that condensates formed by multivalent proteins share features with network fluids formed by systems such as patchy or hairy colloids.
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- Award ID(s):
- 2227268
- PAR ID:
- 10564800
- Publisher / Repository:
- Nature Publishing Group
- Date Published:
- Journal Name:
- Nature Communications
- Volume:
- 15
- Issue:
- 1
- ISSN:
- 2041-1723
- Format(s):
- Medium: X
- Sponsoring Org:
- National Science Foundation
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