Total syntheses of the reported structures of the rhamnofolane diterpene natural products curcusones I and J in racemic form were achieved. The synthetic strategy features a novel tandem gold‐catalyzed furan formation and furan–allene [4+3] cycloaddition to build the 5,7‐fused ring system with an oxa‐bridge in one step, and a stereoselective
This content will become publicly available on August 8, 2025
- Award ID(s):
- 1935327
- PAR ID:
- 10567266
- Publisher / Repository:
- Royal Society of Chemistry
- Date Published:
- Journal Name:
- Journal of Materials Chemistry C
- Volume:
- 12
- Issue:
- 31
- ISSN:
- 2050-7526
- Page Range / eLocation ID:
- 11976 to 11981
- Format(s):
- Medium: X
- Sponsoring Org:
- National Science Foundation
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Abstract exo ‐Diels–Alder reaction to form the 6‐membered ring. The newly developed tandem gold catalysis is quite general and can be scaled up. Our syntheses suggest that structural revisions of curcusones I and J are needed. -
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