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Abstract In designing femoral components, which restore native (i.e., healthy) knee kinematics, the flexion–extension (F-E) axis of the tibiofemoral joint should match that of the native knee. Because the F–E axis is governed by the curvature of the femoral condyles in the sagittal plane, the primary objective was to determine the variation in radii of curvature. Eleven high accuracy three-dimensional (3D) femur models were generated from ultrahigh resolution CT scans. The sagittal profile of each condyle was created. The radii of curvature at 15 deg increments of arc length were determined based on segment circles best-fit to ±15 deg of arc at each increment. Results were standardized to the radius of the best-fit overall circle to 15 deg–105 deg for the femoral condyle having a radius closest to the mean radius. Medial and lateral femoral condyles exhibited multiradius of curvature sagittal profiles where the radius decreased at 30 deg flexion by 10 mm and at 15 deg flexion by 8 mm, respectively. On either side of the decrease, radii of segment circles were relatively constant. Beyond the transition angles where the radii decreased, the anterior-posterior (A-P) positions of the centers of curvature varied 4.8 mm and 2.3 mm for the medial and lateral condyles, respectively. A two-radius of curvature profile approximates the radii of curvature of both native femoral condyles, but the transition angles differ with the transition angle of the medial femoral condyle occurring about 15 deg later in flexion. Owing to variation in A-P positions of centers of curvature, the F-E axis is not strictly fixed in the femur.
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Does spinopelvic alignment affect femoral head cartilage and the proximal femoral physis in slipped capital femoral epiphysis? A finite element analysis
Background: Slipped capital femoral epiphysis is a prevalent pediatric hip disorder. Recent studies suggest the spine’s sagittal profile may influence the proximal femoral growth plate’s slippage, an aspect not extensively explored. This study utilizes finite element analysis to investigate how various spinopelvic alignments affect shear stress and growth plate slip. Methods: A finite element model was developed from CT scans of a healthy adult male lumbar spine, pelvis, and femurs. The model was subjected to various sagittal alignments through reorientation. Simulations of two-leg stance, one-leg stance, walking heel strike, ascending stairs heel strike, and descending stairs heel strike were conducted. Parameters measured included hip joint contact area, stress, and maximum growth plate Tresca (shear) stress. Findings: Posterior pelvic tilt cases indicated larger shear stresses compared to the anterior pelvic tilt variants except in two leg stance. Two leg stance resulted in decreases in the posterior tilted pelvi variants hip contact and growth plate Tresca stress compared to anterior tilted pelvi, however a combination of posterior pelvic tilt and high pelvic incidence indicated larger shear stresses on the growth plate. One leg stance and heal strike resulted in higher shear stress on the growth plate in posterior pelvic tilt variants compared to anterior pelvic tilt, with a combination of posterior pelvic tilt and high pelvic incidence resulting in the largest shear. Interpretation: Our findings suggest that posterior pelvic tilt and high pelvic incidence may lead to increased shear stress at the growth plate. Activities performed in patients with these alignments may predispose to biomechanical loading that shears the growth plate, potentially leading to slip.
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- Award ID(s):
- 1916636
- PAR ID:
- 10570267
- Publisher / Repository:
- Elsevier
- Date Published:
- Journal Name:
- Clinical Biomechanics
- Volume:
- 116
- Issue:
- C
- ISSN:
- 0268-0033
- Page Range / eLocation ID:
- 106269
- Format(s):
- Medium: X
- Sponsoring Org:
- National Science Foundation
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Abstract The femoral neck axis serves as a critical parameter in evaluating hip joint health, particularly in the pediatric population. Commonly used metrics for evaluating femoral torsion, such as the femoral neck-shaft and femoral anteversion angles, rely heavily on precise definitions of the position and orientation of the femoral neck axis. Current measurement methods employing radiographs and performing two-dimensional (2D) measurements on computed tomography (CT) scans are susceptible to errors due to their reliance on reader experience and the inherent limitations in 2D measurements. We hypothesized that utilizing volumetric data would mitigate these errors and enable more accurate and reproducible measurements of the femoral neck axis using the femoral anteversion and femoral neck-shaft angles. To test this hypothesis, we analyzed a historical collection of postmortem infant femoral and pelvic bones (28 hips) aged 0 to 6.5 months, with an average estimated age of 4.68 ± 1.80 months. Our findings revealed an average neck-shaft angle of 128.00 ± 4.92 deg and femoral anteversion angle of 35.56 ± 11.68 deg across all femurs, consistent with literature values. These measurements obtained from volumetric image data were found to be repeatable and reliable compared to conventional methods. Our study suggests that the proposed methodology offers a standardized approach for obtaining repeatable and reproducible measurements, thus potentially enhancing diagnostic accuracy and clinical decision-making in assessing hip developmental conditions in pediatric patients.more » « less
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Abstract The Eastern California shear zone is a complex set of dextral faults that accommodates significant plate motion and has produced large earthquakes. The evolution of this system and why it consists of closely spaced, irregular faults that fail in multi‐fault ruptures are not well understood. Here we analyze the geometry, spatial distribution, and Quaternary slip activity of right‐lateral faults in the southern Mojave block. We find these faults are oriented favorably for accommodating regional dextral plate motion and do not show evidence of replacement following counterclockwise rotation to unfavorable positions, although activity may be migrating westward as previously proposed. We also confirm that the shear zone is transpressive, with widespread restraining bends, distributed convergent deformation, and significant impact on near‐fault topography. Observations also show that faults are geometrically complex, as represented by along‐strike variability in fault strike. We document a correlation between strike variability and fault activity (slip rate or net slip), which is evident within the shear zone as well as for a control group of other faults. We suggest that strike variability represents a form of geometric roughness, which may inhibit fault slip and result in complex ruptures, slip‐strengthening behavior, and a prevalence of off‐fault deformation. Other factors, including preexisting crustal fabric, edge effects, and changes in the stress field, may further complicate kinematics. These results suggest that faults of the shear zone are still juvenile and somewhat unique, yet offer an important window into how broadly distributed shear may evolve into a through‐going continental transform system.more » « less
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Physics-based dynamic rupture simulations are valuable for assessing the seismic hazard in the Cascadia subduction zone (CSZ), but require assumptions about fault stress and material properties. Geodetic slip deficit models (SDMs) may provide information about the initial stresses governing megathrust earthquake dynamics. We present a unified workflow linking SDMs to 3D dynamic rupture simulations, and 22 rupture scenarios to unravel the dynamic trade-offs of assumptions for SDMs, rigidity, and pore fluid pressure. We find that margin-wide rupture, an earthquake that ruptures the entire length of the plate boundary, requires a large slip deficit in the central CSZ. Comparisons between Gaussian and smoother, shallow-coupled SDMs show significant differences in stress distributions and rupture dynamics. Variations in depth-dependent rigidity cause competing effects, particularly in the near-trench region. Higher overall rigidity can increase fault slip but also result in lower initial shear stresses, inhibiting slip. The state of pore fluid pressure is crucial in balancing SDM-informed initial shear stresses with realistic dynamic rupture processes, especially assuming small recurrence time scaling factors. This study highlights the importance of self-consistent assumptions for rigidity and initial stresses between geodetic, structural, and dynamic rupture models, providing a foundation for future simulations of ground motions and tsunami generation.more » « less
- Free Publicly Accessible Full Text
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Accepted Manuscript1.0
- Journal Article:
- https://doi.org/10.1016/j.clinbiomech.2024.106269
