Abstract Patients with influenza and SARS-CoV2/Coronavirus disease 2019 (COVID-19) infections have a different clinical course and outcomes. We developed and validated a supervised machine learning pipeline to distinguish the two viral infections using the available vital signs and demographic dataset from the first hospital/emergency room encounters of 3883 patients who had confirmed diagnoses of influenza A/B, COVID-19 or negative laboratory test results. The models were able to achieve an area under the receiver operating characteristic curve (ROC AUC) of at least 97% using our multiclass classifier. The predictive models were externally validated on 15,697 encounters in 3125 patients available on TrinetX database that contains patient-level data from different healthcare organizations. The influenza vs COVID-19-positive model had an AUC of 98.8%, and 92.8% on the internal and external test sets, respectively. Our study illustrates the potentials of machine-learning models for accurately distinguishing the two viral infections. The code is made available athttps://github.com/ynaveena/COVID-19-vs-Influenzaand may have utility as a frontline diagnostic tool to aid healthcare workers in triaging patients once the two viral infections start cocirculating in the communities.
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Harnessing the Power of Vocal Signals in COVID-19 Detection Utilizing Machine Learning
The global COVID-19 pandemic has strained healthcare systems and highlighted the need for accessible and efficient diagnostic methods. Traditional diagnostic tools, such as nasal swabs and biosensors, while accurate, pose significant logistical challenges and high costs, limiting their scalability. This paper explores an alternative, non-invasive approach to COVID-19 detection using machine learning algorithms to analyze vocal patterns, particularly cough and breathing sounds. Leveraging a publicly available dataset, we developed machine learning models capable of classifying audio samples as COVID-19 positive or negative. Our models achieve an AUC of up to 85% and an F1- score of 81%, demonstrating the potential of machine learning in enabling rapid, cost-effective COVID-19 diagnosis. These findings suggest that audio-based diagnostics could be a practical and scalable solution, particularly in resource-limited settings where traditional methods are less feasible.
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- Award ID(s):
- 2334391
- PAR ID:
- 10570734
- Publisher / Repository:
- IEEE
- Date Published:
- ISBN:
- 979-8-3503-6248-0
- Page Range / eLocation ID:
- 4564 to 4570
- Subject(s) / Keyword(s):
- Coronavirus COVID-19 machine learning coughs breathing vocal signal analysis COVID-19 detection
- Format(s):
- Medium: X
- Location:
- Washington, DC, USA
- Sponsoring Org:
- National Science Foundation
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