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Modulation of Heme Peroxo Nucleophilicities with Axial Ligands Reveal Key Insights into the Mechanistic Landscape of Nitric Oxide Synthase
Mid-valent heme-oxygen intermediates are central to a medley of pivotal physiological transformations in humans, and such systems are increasingly becoming more relevant therapeutic targets for challenging disease conditions. Nonetheless, precise...
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- PAR ID:
- 10586055
- Publisher / Repository:
- Royal Society of Chemistry
- Date Published:
- Journal Name:
- Chemical Science
- ISSN:
- 2041-6520
- Format(s):
- Medium: X
- Sponsoring Org:
- National Science Foundation
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