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This content will become publicly available on May 27, 2026

Title: An implementation of neural simulation-based inference for parameter estimation in ATLAS
Abstract Neural simulation-based inference (NSBI) is a powerful class of machine-learning-based methods for statistical inference that naturally handles high-dimensional parameter estimation without the need to bin data into low-dimensional summary histograms. Such methods are promising for a range of measurements, including at the Large Hadron Collider, where no single observable may be optimal to scan over the entire theoretical phase space under consideration, or where binning data into histograms could result in a loss of sensitivity. This work develops a NSBI framework for statistical inference, using neural networks to estimate probability density ratios, which enables the application to a full-scale analysis. It incorporates a large number of systematic uncertainties, quantifies the uncertainty due to the finite number of events in training samples, develops a method to construct confidence intervals, and demonstrates a series of intermediate diagnostic checks that can be performed to validate the robustness of the method. As an example, the power and feasibility of the method are assessed on simulated data for a simplified version of an off-shell Higgs boson couplings measurement in the four-lepton final states. This approach represents an extension to the standard statistical methodology used by the experiments at the Large Hadron Collider, and can benefit many physics analyses.  more » « less
Award ID(s):
2111244
PAR ID:
10616446
Author(s) / Creator(s):
Publisher / Repository:
IOP Publishing
Date Published:
Journal Name:
Reports on Progress in Physics
Volume:
88
Issue:
6
ISSN:
0034-4885
Page Range / eLocation ID:
067801
Format(s):
Medium: X
Sponsoring Org:
National Science Foundation
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