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Sulfur fluoride exchange with carbon pronucleophiles
This study reports the introduction of alkyl carbon pronucleophiles to sulfur fluoride exchange (SuFEX) exhibited by the synthesis of aryl alkyl sulfones. Parallel medicinal chemistry (PMC) is exemplified with amides, and late-stage functionalization is demonstrated with a drug scaffold.
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- Award ID(s):
- 2202693
- PAR ID:
- 10645097
- Publisher / Repository:
- The Royal Society of Chemistry
- Date Published:
- Journal Name:
- Chemical Science
- Volume:
- 16
- Issue:
- 35
- ISSN:
- 2041-6520
- Page Range / eLocation ID:
- 16063 to 16069
- Format(s):
- Medium: X
- Sponsoring Org:
- National Science Foundation
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