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The title compound C23H23N2Te+·PF6−, is a monoclinic polymorph of the previously reported triclinic structure [Calitreeet al.(2007).Organometallics,26, 6248–6257]. In the crystal, parallel offset π–π stacking [shortest centroid–centroid separation = 3.9620 (9) Å] and ionic interactions help to establish the packing.
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This content will become publicly available on May 1, 2026
Dichlorido{(E)-N,N-dimethyl-2-[phenyl(pyridin-2-yl)methylidene]hydrazine-1-carbothioamide}cadmium(II)
The structure of the title compound, [CdCl2(C15H16N4S)], at 100 K has monoclinic (P21/c) symmetry. The compound has a layer structure and is a 1:1 complex of the organic ligand and cadmium chloride. The ligand, 3,3-dimethyl-1-[(E)-[phenyl(pyridine-2-yl)methylidene]amino]thiourea (L, Bp44mT), is of interest with respect to anticancer activity, antiviral properties and potential use in conditions of iron overload, from hemochromatosis or from multiple transfusions in hematological disorders such as sickle cell disease or beta thalassemia. This study is aimed at uncovering the basis of selectivity of the ligand as a chelator and for lead optimization. We also examine the ligand's potential use in treating heavy metal poisoning from cadmium, arsenic, lead or mercury, and for environmental remediation. The crystal structure exhibits no intermolecular or intramolecular hydrogen bonding with the supramolecular features being driven by hydrophobic, π–π and long-range dispersion forces.
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- Award ID(s):
- 2117502
- PAR ID:
- 10656165
- Publisher / Repository:
- International Union of Crystallography
- Date Published:
- Journal Name:
- IUCrData
- Volume:
- 10
- Issue:
- 5
- ISSN:
- 2414-3146
- Page Range / eLocation ID:
- x250464
- Subject(s) / Keyword(s):
- crystal structure post-industrial pollution riverways and food chain thiosemicarbazone heterocycle ligands heavy metals
- Format(s):
- Medium: X
- Sponsoring Org:
- National Science Foundation
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