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ABSTRACT Scientific misinformation is a defining challenge of our time. As public trust in science declines and falsehoods spread faster than facts, the scientific community must rethink its role in public discourse. This Perspective draws on a scenario-based workshop entitled ‘Truth Matters: Strengthening Science Communication to Counter Misinformation’, conducted at the 20th International Congress of Developmental Biology in San Juan, Puerto Rico (June 2025), designed to train scientists in emotionally attuned, culturally responsive and effective communication strategies. At the joint conference with the International Society of Developmental Biology, the Society for Developmental Biology and the Latin American Society for Developmental Biology, we explored why misinformation persists, how identity and social belonging shape belief, and why empathy, not just evidence, is essential to making truth resonate. Here, we offer a call to action along with practical tools: to make scientific knowledge meaningful, we must communicate effectively and ensure it resonates with the broader public.