Note: When clicking on a Digital Object Identifier (DOI) number, you will be taken to an external site maintained by the publisher.
Some full text articles may not yet be available without a charge during the embargo (administrative interval).
What is a DOI Number?
Some links on this page may take you to non-federal websites. Their policies may differ from this site.
-
Free, publicly-accessible full text available April 27, 2026
-
Socioeconomic inequalities complicate the local governance process, especially in low- and middle-income countries. With limited public resources and high socioeconomic inequalities, local governments can find themselves in a vicious circle of increasing inequalities, declining ability to address needs, and mounting social problems. Here, we investigate a possible way out of the vicious circle: policy interventions that help reduce the strain of inequality on local government responsiveness. We argue that interventions are effective in dampening the strain when these recognize the leadership role of local government officials. To test our arguments, we analyze longitudinal data on how citizen satisfaction with local governments varies in 56 Chilean territories over a 15-year period. We find that high socioeconomic inequality is associated with lower overall citizen satisfaction with local government performance, but exogenous interventions can dampen this association when local politicians take the lead in planning and implementing the interventions.more » « lessFree, publicly-accessible full text available April 1, 2026
-
SUMMARY Plants synthesize an array of volatile compounds, many of which serve ecological roles in attracting pollinators, deterring herbivores, and communicating with their surroundings. Methyl anthranilate (MeAA) is an anti‐herbivory defensive volatile responsible for grape aroma that is emitted by several agriculturally relevant plants, including citrus, grapes, and maize. Unlike maize, which uses a one‐step anthranilate methyltransferase (AAMT), grapes have been thought to use a two‐step pathway for MeAA biosynthesis. By mining available transcriptomics data, we identified two AAMTs inVitis vinifera(wine grape), as well as one ortholog in “Concord” grape. Many angiosperms methylate the plant hormone salicylic acid (SA) to produce methyl salicylate, which acts as a plant‐to‐plant communication molecule. Because theCitrus sinensis(sweet orange) SA methyltransferase can methylate both anthranilate (AA) and SA, we used this enzyme to examine the molecular basis of AA activity by introducing rational mutations, which identified several active site residues that increase activity with AA. Reversing this approach, we introduced mutations that imparted activity with SA in the maize AAMT, which uncovered different active site residues from those in the citrus enzyme. Sequence and phylogenetic analysis revealed that one of theVitisAAMTs shares an ancestor with jasmonic acid methyltransferases, similar to the AAMT from strawberry (Frageriasp.). Collectively, these data demonstrate the molecular mechanisms underpinning AA activity across methyltransferases and identify one‐step enzymes by which grapes synthesize MeAA.more » « less
An official website of the United States government
