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Despite their structural similarities, ortho-phenylenes and 2,3-quinoxalinylenes (i.e., poly(quinoxaline-2,3-diyl)s), well known as foldamers and helical polymers, respectively, exhibit distinctly different conformational behavior. o-Phenylenes tend to fold into compact helices with every fourth ring stacked, whereas 2,3-quinoxalinylenes favor extended helices with no backbone stacking. To understand this difference, we have studied short o-arylenes with different sequences of benzene and pyrazine units. Through a combination of crystallography, variable-temperature NMR spectroscopy, and DFT calculations, we find that pyrazines favor extended helical conformations as a result of two effects. First, within an o-arylene architecture, pyrazines experience weaker arene–arene interactions. Cofacial packing of the rings is therefore less favorable. Second, bipyrazine units lead to an increase in vibrational entropy for extended conformers. Consequently, at higher temperatures (including room temperature), extended helices are favored for the heterocycle-containing systems. 

Internet-of-Things (IoT) approaches are continually introducing new sensors into the fields of agriculture and animal welfare. The application of multi-sensor data fusion to these domains remains a complex and open-ended challenge that defies straightforward optimization, often requiring iterative testing and refinement. To respond to this need, we have created a new open-source framework as well as a corresponding Python tool which we call the “Data Fusion Explorer (DFE)”. We demonstrated and evaluated the effectiveness of our proposed framework using four early-stage datasets from diverse disciplines, including animal/environmental tracking, agrarian monitoring, and food quality assessment. This included data across multiple common formats including single, array, and image data, as well as classification or regression and temporal or spatial distributions. We compared various pipeline schemes, such as low-level against mid-level fusion, or the placement of dimensional reduction. Based on their space and time complexities, we then highlighted how these pipelines may be used for different purposes depending on the given problem. As an example, we observed that early feature extraction reduced time and space complexity in agrarian data. Additionally, independent component analysis outperformed principal component analysis slightly in a sweet potato imaging dataset. Lastly, we benchmarked the DFE tool with respect to the Vanilla Python3 packages using our four datasets’ pipelines and observed a significant reduction, usually more than 50%, in coding requirements for users in almost every dataset, suggesting the usefulness of this package for interdisciplinary researchers in the field. 

Synopsis Seventy percent of mammals copulate using repeated pelvic thrusting, while the transfer of sperm requires just a single intromission. Why did thrusting evolve to be the dominant form of sexual intercourse? In this study, we investigate how the rate of sexual pelvic thrusting changes with body size. By analyzing films of copulating mammals, from mice Mus musculus to elephants Elephantidae, we find that bigger animals thrust slower. The rate of pelvic thrusting decreases from 6 Hz for the pocket mouse Pergonathus to 1.3–1.8 Hz for humans to an absence of thrusting for the rhino Rhinocerotidae and elephant Elephantidae families. To understand this dependence on body size, we consider the spring-like behavior of the legs, which is associated with the elasticity of the body's muscles, tendons, and ligaments. For both running and thrusting, greater displacment and energy savings can be achieved if the system is oscillated at its resonant or natural frequency. Resonant frequencies, as measured through previous studies of running in dogs Canis familiaris and horses Equus ferus caballus, show good agreement with sexual thrusting frequencies. Running and sexual thrusting have nothing in common from a behavioral perspective, but from a physical perspective, they are both constrained by the same musculoskeletal systems, and both take advantage of resonance. Our findings may provide improved treatments for human sexual dysfunction as well as improving breeding strategies for domestic mammals. 

The California blackworm,Lumbriculus variegatus, lives underwater and latches its tail to the water surface for respiration and stability. Little is known about the upward force generated by this posture. In this combined experimental and theoretical study, we visualize the menisci shape for blackworms and blackworm mimics, composed of smooth and corrugated epoxy rods. We apply previous theoretical models for floating cylinders to predict the upward force and safety factor of blackworms as well as other organisms such as mosquito larvae, leeches and aquatic snails. Understanding the upward forces of organisms that latch onto the water surface may help to understand the evolution of interfacial attachment and inspire biomimetic robots. 

This work presents a multiscale study of the uniaxial compression of Si pillars, with diameters ranging from 50 nm to 360 nm, using the Concurrent Atomistic-Continuum (CAC) method. The simulations reproduce the brittle and ductile deformation behaviors of Si pillars observed in experiments. For defect-free Si pillars compressed by a perfectly smooth flat punch with a repulsive force field to reflect an assumed rigid indenter, dislocations are nucleated from the corner of the bottom surface for pillars with diameters of 100 nm and below, while for pillars with diameters of 220 nm and above, dislocations nucleate from the top surface; multiple slip systems are activated in all pillars except for the pillar with a diameter of 50 nm. A strong size effect is thus demonstrated with regard to the nucleation of dislocations. Another key finding is the critical role of defects on the indenter surface. For a perfectly flat indenter, all the defect-free Si pillars with diameters ranging from 50 nm to 360 nm exhibit ductile deformation. By contrast, for an indenter with surface steps, all pillars with diameters of 100 nm and above deform in a brittle manner. These surface steps cause sequential nucleation of dislocations and activation of two slip systems, leading to dislocation intersection and formation of a sessile Lomer lock. Continued pileups of dislocations against the Lomer lock lead to the initiation of a crack at the intersection. The deformation mechanism underlying the crack formation is thus demonstrated.