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Abstract The success of current and future-generation neutrinoless double beta (0νββ) decay experiments relies on the ability to eliminate or reduce extraneous backgrounds. In addition to constructing experiments using radiopure materials and handling in underground laboratories, it is necessary to understand and reduce known backgrounds in data analysis. The Large Enriched Germanium Experiment for Neutrinoless double beta Decay (LEGEND) is searching for 0νββdecay using⁷⁶Ge-enriched high-purity germanium (HPGe) detectors submerged in an active liquid argon (LAr) veto. A significant background in LEGEND is surface events from shallowly-impinging radiation on detector surfaces. In this paper we introduce the Collimated Alphas, Gammas, and Electrons (CAGE) scanning system, an internal-source scanning vacuum cryostat, designed to perform studies of surface events on sensitive surfaces of HPGe in a surface-lab. CAGE features a collimated radionuclide source inside a movable infrared shield that is able to perform precision scans of detector surfaces by utilizing three independent motor stages for source positioning. This allows detailed studies of pulse shapes as a function of source position and incident angle, where defining features can be extracted and exploited for removing surface backgrounds in data analysis in LEGEND. In this paper, we describe CAGE and demonstrate its performance with a commissioning run with²⁴¹Am. The commissioning run was completed with the source at normal incidence, and we estimate a beam spot precision of 3.1 mm, which includes positioning uncertainties and the beam-spot size. Using the 59.5 keV gamma population from²⁴¹Am, we show that low-energy photon events near the passivated surface feature risetimes that increase with radial distance from the detector center. We suggest a specific metric that can be used to discriminate low-energy gamma backgrounds in LEGEND with the similar characteristics (e.g. contamination from²¹⁰Pb). 

Abstract Neutrinoless double-beta decay ( $0\nu \beta \beta$ ) is a rare nuclear process that, if observed, will provide insight into the nature of neutrinos and help explain the matter-antimatter asymmetry in the Universe. The large enriched germanium experiment for neutrinoless double-beta decay (LEGEND) will operate in two phases to search for $0\nu \beta \beta$ . The first (second) stage will employ 200 (1000) kg of High-Purity Germanium (HPGe) enriched in⁷⁶Ge to achieve a half-life sensitivity of 10²⁷(10²⁸) years. In this study, we present a semi-supervised data-driven approach to remove non-physical events captured by HPGe detectors powered by a novel artificial intelligence model. We utilize affinity propagation to cluster waveform signals based on their shape and a support vector machine to classify them into different categories. We train, optimize, and test our model on data taken from a natural abundance HPGe detector installed in the Full Chain Test experimental stand at the University of North Carolina at Chapel Hill. We demonstrate that our model yields a maximum sacrifice of physics events of ${0.024}_{-0.003}^{+0.004}\mathrm{\%}$ after data cleaning. Our model is being used to accelerate data cleaning development for LEGEND-200 and will serve to improve data cleaning procedures for LEGEND-1000. 

$\text{DMRadio-}{\mathrm{m}}^3$ is an experimental search for dark matter axions. It uses a solenoidal dc magnetic field to convert an axion dark-matter signal to an ac electromagnetic response in a coaxial copper pickup. The current induced by this axion signal is measured by dc SQUIDs. $\text{DMRadio-}{\mathrm{m}}^3$ is designed to be sensitive to Kim-Shifman-Vainshtein-Zakharov (KSVZ) and Dine-Fischler-Srednicki-Zhitnisky (DFSZ) QCD axion models in the 10–200 MHz ( $41\mathrm{neV}/c^2–0.83\mathrm{\mu }\mathrm{eV}/c^2$ ) range, and to axions with $g_{a\gamma \gamma }=g_{a\gamma \gamma ,\mathrm{DFSZ}}\left(30\mathrm{MHz}\right)=1.87\times {10}^{-17}{\mathrm{GeV}}^{-1}$ over 5–30 MHz as an extended goal. In this work, we present the electromagnetic modeling of the response of the experiment to an axion signal over the full frequency range of $\text{DMRadio-}{\mathrm{m}}^3$ , which extends from the low-frequency, lumped-element limit to a regime where the axion Compton wavelength is only a factor of 2 larger than the detector size. With these results, we determine the live time and sensitivity of the experiment. The primary science goal of sensitivity to DFSZ axions across 30–200 MHz can be achieved with a $3\sigma$ live scan time of 2.9 years. 

76Ge can ββ decay into three possible excited states of 76Se, with the emission of two or, if the neutrino is Majorana, zero neutrinos. None of these six transitions have yet been observed. The Majorana Demonstrator was designed to study ββ decay of 76Ge using a low background array of high purity germanium detectors. With 98.2 kg-y of isotopic exposure, the Demonstrator sets the strongest half-life limits to date for all six transition modes. For 2νββ to the 0+ state of 76Se, this search has begun to probe for the first time half-life values predicted using modern many-body nuclear theory techniques, setting a limit of T_1/2 > 1.5e24 y (90% CL). 

Abstract Serial x-ray crystallography can uncover binding events, and subsequent chemical conversions occurring during enzymatic reaction. Here, we reveal the structure, binding and cleavage of moxalactam antibiotic bound to L1 metallo-β-lactamase (MBL) from Stenotrophomonas maltophilia . Using time-resolved serial synchrotron crystallography, we show the time course of β-lactam hydrolysis and determine ten snapshots (20, 40, 60, 80, 100, 150, 300, 500, 2000 and 4000 ms) at 2.20 Å resolution. The reaction is initiated by laser pulse releasing Zn 2+ ions from a UV-labile photocage. Two metal ions bind to the active site, followed by binding of moxalactam and the intact β-lactam ring is observed for 100 ms after photolysis. Cleavage of β-lactam is detected at 150 ms and the ligand is significantly displaced. The reaction product adjusts its conformation reaching steady state at 2000 ms corresponding to the relaxed state of the enzyme. Only small changes are observed in the positions of Zn 2+ ions and the active site residues. Mechanistic details captured here can be generalized to other MBLs. 

The background index (BI) is an important quantity to project and calculate the half-life sensitivity of neutrinoless double-𝛽 decay (0⁢𝜈⁢𝛽⁢𝛽) experiments. An analysis framework is presented to calculate the BI using the specific activities, masses, and simulated efficiencies of an experiments components as distributions. This Bayesian framework includes a unified approach to combine specific activities from assay. Monte Carlo uncertainty propagation is used to build a BI distribution from the specific activity, mass, and efficiency distributions. This method is applied to the Majorana Demonstrator, which deployed arrays of high-purity Ge detectors enriched in 76Ge to search for 0⁢𝜈⁢𝛽⁢𝛽. The original assay-based projection is requantified in the new framework, using the as-built geometry of the Demonstrator and additional assay information. While 47% higher than the original projection, the resulting BI of [8.95±0.36]×10−4cts/(keVkgyr) from the 232Th and 238U decay chains does not account for the higher-than-expected BI observed by the Demonstrator. This method enables us to demonstrate the statistical incompatibility between the Demonstrator's observed background and the assay results. 

Charge conservation and the Pauli exclusion principle result from fundamental symmetries in the standard model of particle physics, and are typically taken as axiomatic. High-precision tests for small violations of these symmetries could point to new physics. Here we consider three models for violation of these processes, which would produce detectable ionization in the high-purity germanium detectors of the MAJORANA DEMONSTRATOR experiment. Using a 37.5 kg yr exposure, we report a lower limit on the electron mean lifetime, improving the previous best limit for the e->nununu decay channel by more than an order of magnitude. We also present searches for two types of violation of the Pauli exclusion principle, setting limits on the probability of an electron to be found in a symmetric quantum state. 

Abstract TheMajorana Demonstratorwas a search for neutrinoless double-beta decay (0νββ) in the⁷⁶Ge isotope. It was staged at the 4850-foot level of the Sanford Underground Research Facility (SURF) in Lead, SD. The experiment consisted of 58 germanium detectors housed in a low background shield and was calibrated once per week by deploying a²²⁸Th line source for 1 to 2 hours. The energy scale calibration determination for the detector array was automated using custom analysis tools. We describe the offline procedure for calibration of theDemonstratorgermanium detectors, including the simultaneous fitting of multiple spectral peaks, estimation of energy scale uncertainties, and the automation of the calibration procedure.