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  1. Strong interactions and topology drive a wide variety of correlated ground states. Some of the most interesting of these ground states, such as fractional quantum Hall states and fractional Chern insulators, have fractionally charged quasiparticles. Correlations in these phases are captured by the binding of electrons and vortices into emergent particles called composite fermions. Composite fermion quasiparticles are randomly localized at high levels of disorder and may exhibit charge order when there is not too much disorder in the system. However, more complex correlations are predicted when composite fermion quasiparticles cluster into a bubble, and then these bubbles order on a lattice. Such a highly correlated ground state is termed the bubble phase of composite fermions. Here we report the observation of such a bubble phase of composite fermions, evidenced by the re-entrance of the fractional quantum Hall effect. We associate this re-entrance with a bubble phase with two composite fermion quasiparticles per bubble. Our results demonstrate the existence of a new class of strongly correlated topological phases driven by clustering and charge ordering of emergent quasiparticles. 
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  2. Abstract

    Interferons control viral infection by inducing the expression of antiviral effector proteins encoded by interferon‐stimulated genes (ISGs). The field has mostly focused on identifying individual antiviral ISG effectors and defining their mechanisms of action. However, fundamental gaps in knowledge about the interferon response remain. For example, it is not known how many ISGs are required to protect cells from a particular virus, though it is theorized that numerous ISGs act in concert to achieve viral inhibition. Here, we used CRISPR‐based loss‐of‐function screens to identify a markedly limited set of ISGs that confer interferon‐mediated suppression of a model alphavirus, Venezuelan equine encephalitis virus (VEEV). We show via combinatorial gene targeting that three antiviral effectors—ZAP, IFIT3, and IFIT1—together constitute the majority of interferon‐mediated restriction of VEEV, while accounting for < 0.5% of the interferon‐induced transcriptome. Together, our data suggest a refined model of the antiviral interferon response in which a small subset of “dominant” ISGs may confer the bulk of the inhibition of a given virus.

     
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  3. Abstract

    This paper presents the genetic algorithm (GA) and particle swarm optimization (PSO) based frequency regulation for a wind‐based microgrid (MG) using reactive power balance loop. MG, operating from squirrel cage induction generator (SCIG), is employed for exporting the electrical power from wind turbines, and it needs reactive power which may be imported from the grid. Additional reactive power is also required from the grid for the load, directly coupled with such a distributed generator (DG) plant. However, guidelines issued by electric authorities encourage MGs to arrange their own reactive power because such reactive power procurement is defined as a local area problem for power system studies. Despite the higher cost of compensation, static synchronous compensator (STATCOM) is a fast‐acting FACTs device for attending to these reactive power mismatches. Reactive power control can be achieved by controlling reactive current through the STATCOM. This can be achieved with modification in current controller scheme of STATCOM. STATCOM current controller is designed with reactive power load balance for the proposed microgrid in this paper. Further, gain values of the PI controller, required in the STATCOM model, are selected first with classical methods. In this classical method, iterative procedures which are based on integral square error (ISE), integral absolute error (IAE), and integral square of time error (ISTE) criteria are developed using MATLAB programs. System performances are further investigated with GA and PSO based control techniques and their acceptability over classical methods is diagnosed. Results in terms of converter frequency deviation show how the frequency remains under the operating boundaries as allowed by IEEE standards 1159:1995 and 1250:2011 for integrating renewable‐based microgrid with grid. Real and reactive power management and load current total harmonic distortions verify the STATCOM performance in MG. The results are further validated with the help of recent papers in which frequency regulation is investigated for almost similar power system models. The compendium for this work is as following: (i) modelling of wind generator‐based microgrid using MATLAB simulink library, (ii) designing of STATCOM current controller with PI controller, (iii) gain constants estimation using classical, GA and PSO algorithm through a developed m codes and their interfacing with proposed simulink model, (v) dynamic frequency responses for proposed grid connected microgrid during starting and load perturbations, (vi) verification of system performance with the help of obtained real and reactive power management between STATCOM and grid, and (vii) validation of results with available literature.

     
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  4. One of the most fundamental questions in ecology is how many species inhabit the Earth. However, due to massive logistical and financial challenges and taxonomic difficulties connected to the species concept definition, the global numbers of species, including those of important and well-studied life forms such as trees, still remain largely unknown. Here, based on global ground-sourced data, we estimate the total tree species richness at global, continental, and biome levels. Our results indicate that there are ∼73,000 tree species globally, among which ∼9,000 tree species are yet to be discovered. Roughly 40% of undiscovered tree species are in South America. Moreover, almost one-third of all tree species to be discovered may be rare, with very low populations and limited spatial distribution (likely in remote tropical lowlands and mountains). These findings highlight the vulnerability of global forest biodiversity to anthropogenic changes in land use and climate, which disproportionately threaten rare species and thus, global tree richness. 
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