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Colell, Johannes F.; Logan, Angus W.; Zhou, Zijian; Lindale, Jacob R.; Laasner, Raul; Shchepin, Roman V.; Chekmenev, Eduard Y.; Blum, Volker; Warren, Warren S.; Malcolmson, Steven J.; et al (, Chemical Communications)Here we report on chelating ligands for Signal Amplification By Reversible Exchange (SABRE) catalysts that permit hyperpolarisation on otherwise sterically hindered substrates. We demonstrate 1 H enhancements of ∼100-fold over 8.5 T thermal for 2-substituted pyridines, and smaller, yet significant enhancements for provitamin B 6 and caffeine. We also show 15 N-enhancements of ∼1000-fold and 19 F-enhancements of 30-fold.more » « less
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