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Creators/Authors contains: "Li, Minghe"

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  1. ; ; ; ; (, Analytical Chemistry)
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  2. ; ; (, Analytical Chemistry)
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  3. ; ; ; ; ; ; ; ; ; ; et al (, Analytical Chemistry)
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  4. ; ; ; ; ; ; (, Analytical Chemistry)
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  5. ; ; ; ; ; (, Acta Crystallographica Section D Structural Biology)
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    The depth of field (DoF) was extended 2.8-fold to achieve rapid crystal screening by retrofitting a custom-designed micro-retarder array (µRA) in the optical beam path of a nonlinear optical microscope. The merits of the proposed strategy for DoF enhancement were assessed in applications of second-harmonic generation imaging of protein crystals. It was found that DoF extension increased the number of crystals detected while simultaneously reducing the number of ` z -slices' required for screening. Experimental measurements of the wavelength-dependence of the extended DoF were in excellent agreement with theoretical predictions. These results provide a simple and broadly applicable approach to increase the throughput of existing nonlinear optical imaging methods for protein crystal screening. 
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  6. ; ; ; ; ; ; ; ; ; (, Journal of the American Chemical Society)
    null (Ed.)
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