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Creators/Authors contains: "Marzieh Ataei, Mohammad Aghaamoo"

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  1. In this work, we apply theoretical, computational and experimental fluid dynamics to characterize hydrodynamics micro-vortices formation in the dispersed phase at the flow-focusing microfluidic droplet generation junction. This interfacial hydrodynamic method can be exploited to trap cells inside the micro-vortices and later release them in a one-to-one manner to achieve high efficiency single-cell encapsulation inside droplets. This passive trap and release mechanism is controlled by the distance between the closed vortex streamline and the liquid-liquid interface (dgap) and, thus, fundamental understanding of the micro-vortices and parameters affecting their formation, trajectory and magnitude is necessary to achieve effective one-to-one encapsulation. 
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