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Creators/Authors contains: "Pu, Lin"

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  1. A chemoselective as well as enantioselective fluorescent probe has been developed to determine both the concentration and enantiomeric composition of the biologically important amino acid histidine by measuring the fluorescence responses when excited at two different wavelengths.
  2. A highly chemoselective as well as enantioselective fluorescent probe has been discovered for the recognition of the acidic amino acids, including glutamic acid and aspartic acid. This study has established a novel amino acid recognition mechanism by an aldehyde-based fluorescent probe.
  3. A series of BINOL-based monoaldehydes have been designed and synthesized as fluorescent probes for l - and d -tryptophan. It is found that in the presence of a diblock copolymer PEG-PLLA, these probes can be encapsulated into micelles which in combination with Zn 2+ have exhibited chemo- and enantioselective fluorescent enhancement with tryptophan in aqueous media.