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The coronavirus pandemic has fostered an explosion of misinformation about the disease, including the risk and effectiveness of vaccination. AI tools for automatic Scientific Claim Verification (SCV) can be crucial to defeat misinformation campaigns spreading through social media channels. However, over the past years, many concerns have been raised about the robustness of AI to adversarial attacks, and the field of automatic scientific claim verification is not exempt. The risk is that such SCV tools may reinforce and legitimize the spread of fake scientific claims rather than refute them. This paper investigates the problem of generating adversarial attacks for SCV tools and shows that it is far more difficult than the generic NLP adversarial attack problem. The current NLP adversarial attack generators, when applied to SCV, often generate modified claims with entirely different meaning from the original. Even when the meaning is preserved, the modification of the generated claim is too simplistic (only a single word is changed), leaving many weaknesses of the SCV tools undiscovered. We propose T5-ParEvo, an iterative evolutionary attack generator, that is able to generate more complex and creative attacks while better preserving the semantics of the original claim. Using detailed quantitative and qualitative analysis, we demonstrate the efficacy of T5-ParEvo in comparison with existing attack generators. 

Cyberattacks on power grids pose significant risks to national security. Power grid attacks typically lead to abnormal readings in power output, frequency, current, and voltage. Due to the interconnected structure of power grids, abnormalities can spread throughout the system and cause widespread power outages if not detected and dealt with promptly. Our research proposes a novel anomaly detection system for power grids that prevents overfitting. We created a network graph to represent the structure of the power grid, where nodes represent power grid components like generators and edges represent connections between nodes such as overhead power lines. We combine the capabilities of Long Short-Term Memory (LSTM) models with a Graph Isomorphism Network (GIN) in a hybrid model to pinpoint anomalies in the grid. We train our model on each category of nodes that serves a similar structural purpose to prevent overfitting of the model. We then assign each node in the graph a unique signature using a GIN. Our model achieved a 99.92% accuracy rate, which is significantly higher than a version of our model without structural encoding, which had an accuracy level of 97.30%. Our model allows us to capture structural and temporal components of power grids and develop an attack detection system with high accuracy without overfitting. 

Ribozymes are RNA molecules that catalyze biochemical reactions. Self-cleaving ribozymes are a common naturally occurring class of ribozymes that catalyze site-specific cleavage of their own phosphodiester backbone. In addition to their natural functions, self-cleaving ribozymes have been used to engineer control of gene expression because they can be designed to alter RNA processing and stability. However, the rational design of ribozyme activity remains challenging, and many ribozyme-based systems are engineered or improved by random mutagenesis and selection ( in vitro evolution). Improving a ribozyme-based system often requires several mutations to achieve the desired function, but extensive pairwise and higher-order epistasis prevent a simple prediction of the effect of multiple mutations that is needed for rational design. Recently, high-throughput sequencing-based approaches have produced data sets on the effects of numerous mutations in different ribozymes (RNA fitness landscapes). Here we used such high-throughput experimental data from variants of the CPEB3 self-cleaving ribozyme to train a predictive model through machine learning approaches. We trained models using either a random forest or long short-term memory (LSTM) recurrent neural network approach. We found that models trained on a comprehensive set of pairwise mutant data could predict active sequences at higher mutational distances, but the correlation between predicted and experimentally observed self-cleavage activity decreased with increasing mutational distance. Adding sequences with increasingly higher numbers of mutations to the training data improved the correlation at increasing mutational distances. Systematically reducing the size of the training data set suggests that a wide distribution of ribozyme activity may be the key to accurate predictions. Because the model predictions are based only on sequence and activity data, the results demonstrate that this machine learning approach allows readily obtainable experimental data to be used for RNA design efforts even for RNA molecules with unknown structures. The accurate prediction of RNA functions will enable a more comprehensive understanding of RNA fitness landscapes for studying evolution and for guiding RNA-based engineering efforts.