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Both crustal velocity and density models provide important constraints for understanding crustal tectonics, composition and magmatic system. However, conventional gravity inversion methods for density models are troubled by poor depth-resolution and non-uniqueness. We apply a joint inversion method to full-waveform ambient noise and gravity data for simultaneously deriving high-resolution 3-D crustal S-wave velocity (Vs) and density models. By constraints of seismic and gravity data, our joint inversion could significantly improve the resolution of density models and reduce the uncertainty on the inversion results. Our method is suitable for any areas especially with low seismicity and can be extended to basin-scale. We apply the method on the seismic and gravity data around the Jingpohu (JPH) volcanic area in Northeast China to obtain high-resolution 3-D crustal Vs and density models, which are subsequently used to build the crustal lithological model. Our models demonstrate that the JPH volcanic group is located near the junction of the Mudanjiang–Yilan and Dunhua–Mishan fault zones and was tectonically controlled by them. A steep crustal-scale mafic intrusion with high Vs and density is present beneath the JPH volcanic group, and we interpret it as the same product as the JPH volcanic basaltic rocks outcropped on the surface by the mantle-sourced magmatic upwelling. Furthermore, none significant molten magma reservoirs with low Vs and density are observed currently within the crust of the JPH volcanic group. Thus, our results support that the JPH volcanic group is a single volcanic genesis with a mantle-only magma source.

 

Rapid urbanization, climate change, and aging infrastructure pose significant challenges to achieving sustainability and resilience goals in urban building energy use. Although retrofitting offers a viable solution to mitigate building energy use, there has been limited analysis of its effects under various weather conditions associated with climate change in urban building energy use simulations. Moreover, certain parameters in energy simulations necessitate extensive auditing or survey work, which is often impractical. This research proposes a framework that integrates various datasets, including building footprints, Lidar data, property appraisals, and street view images, to conduct neighborhood-scale building energy use analysis using the Urban Modeling Interface (UMI), an Urban Building Energy Model (UBEM), in a coastal neighborhood in Galveston, Texas. Seven retrofit plans and three weather conditions are considered in the scenarios of building energy use. The results show that decreasing the U-value of building envelopes helps reduce energy use, while increasing the U-value leads to higher energy consumption in the Galveston neighborhood. This finding provides direction for coastal Texas cities, like Galveston, to update building standards and implement retrofit measures.

 

Proteins, often represented as multi-modal data of 1D sequences and 2D/3D structures, provide a motivating example for the communities of machine learning and computational biology to advance multi-modal representation learning. Protein language models over sequences and geometric deep learning over structures learn excellent single-modality representations for downstream tasks. It is thus desirable to fuse the single-modality models for better representation learning, but it remains an open question on how to fuse them effectively into multi-modal representation learning with a modest computational cost yet significant downstream performance gain. To answer the question, we propose to make use of separately pretrained single-modality models, integrate them in parallel connections, and continuously pretrain them end-to-end under the framework of multimodal contrastive learning. The technical challenge is to construct views for both intra- and inter-modality contrasts while addressing the heterogeneity of various modalities, particularly various levels of semantic robustness. We address the challenge by using domain knowledge of protein homology to inform the design of positive views, specifically protein classifications of families (based on similarities in sequences) and superfamilies (based on similarities in structures). We also assess the use of such views compared to, together with, and composed to other positive views such as identity and cropping. Extensive experiments on enzyme classification and protein function prediction benchmarks demonstrate the potential of domain-informed view construction and combination in multi-modal contrastive learning 

Catastrophic forgetting remains an outstanding challenge in continual learning. Recently, methods inspired by the brain, such as continual representation learning and memory replay, have been used to combat catastrophic forgetting. Associative learning (retaining associations between inputs and outputs, even after good representations are learned) plays an important function in the brain; however, its role in continual learning has not been carefully studied. Here, we identified a two-layer neural circuit in the fruit fly olfactory system that performs continual associative learning between odors and their associated valences. In the first layer, inputs (odors) are encoded using sparse, high-dimensional representations, which reduces memory interference by activating nonoverlapping populations of neurons for different odors. In the second layer, only the synapses between odor-activated neurons and the odor’s associated output neuron are modified during learning; the rest of the weights are frozen to prevent unrelated memories from being overwritten. We prove theoretically that these two perceptron-like layers help reduce catastrophic forgetting compared to the original perceptron algorithm, under continual learning. We then show empirically on benchmark data sets that this simple and lightweight architecture outperforms other popular neural-inspired algorithms when also using a two-layer feedforward architecture. Overall, fruit flies evolved an efficient continual associative learning algorithm, and circuit mechanisms from neuroscience can be translated to improve machine computation.

 

From the beginning of May 2018, the Kilauea Volcano on the island of Hawaii experienced its largest eruption in 200 yr followed by a period of unrest for months. Because hot molten lava entered the ocean from the ocean-entry point near the lower East Rift Zone, the lava–water interaction led to explosions. Some explosions were near the water surface and ejected fragments of lava, also known as lava bombs. In the early morning on 16 July 2018, one of those lava bombs, which was almost the size of a basketball, hit a sightseeing boat and injured 23 people. In this study, we analyzed the hydrophone data recorded from July to mid-September by ocean-bottom seismometers (OBSs) deployed offshore near the ocean entry point to identify and locate the hydroacoustic signals of the lava–water explosions. Acoustic signals of hydrovolcanic explosions are characterized by a short duration (less than a few seconds) and a broad frequency range (at least up to 100 Hz). To automate event detection, a short-term average versus long-term average method was applied to the complete dataset. Approximately 4300 events were detected and located near the coastline and further used to prepare a catalog. The distribution of the lava–water explosions is consistent with the pattern of the offshore lava delta formed during the 2018 eruption. Identifying such hydroacoustic signals recorded by OBSs may provide new avenues of research using various seismoacoustic events associated with volcanic eruptions.

 

Network biology is an interdisciplinary field bridging computational and biological sciences that has proved pivotal in advancing the understanding of cellular functions and diseases across biological systems and scales. Although the field has been around for two decades, it remains nascent. It has witnessed rapid evolution, accompanied by emerging challenges. These stem from various factors, notably the growing complexity and volume of data together with the increased diversity of data types describing different tiers of biological organization. We discuss prevailing research directions in network biology, focusing on molecular/cellular networks but also on other biological network types such as biomedical knowledge graphs, patient similarity networks, brain networks, and social/contact networks relevant to disease spread. In more detail, we highlight areas of inference and comparison of biological networks, multimodal data integration and heterogeneous networks, higher-order network analysis, machine learning on networks, and network-based personalized medicine. Following the overview of recent breakthroughs across these five areas, we offer a perspective on future directions of network biology. Additionally, we discuss scientific communities, educational initiatives, and the importance of fostering diversity within the field. This article establishes a roadmap for an immediate and long-term vision for network biology.

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Liu et al. (2022,https://doi.org/10.1029/2021GL093691) used Rayleigh waves extracted from the cross‐correlation of ambient noise recorded by two stations to monitor the seismic velocity variations associated with the 2018 Kı̄lauea eruption. However, their study ignored the fact that the tremors on the Island of Hawai'i were dominated by a source at the Kı̄lauea summit before the eruption. Close inspection of the waveforms of the station pair PAUD‐STCD shows a simple, mistakenly identified wave traveling direction in Liu et al. (2022,https://doi.org/10.1029/2021GL093691). A correct wave traveling direction agrees with the noise source model, where the dominant tremor source should be at the Kı̄lauea summit. Because of the drastic change in the tremor source after the eruption, the cross‐correlation of the tremor records may reflect predominantly changes in the source rather than in the medium properties between the two stations.