skip to main content
US FlagAn official website of the United States government
dot gov icon
Official websites use .gov
A .gov website belongs to an official government organization in the United States.
https lock icon
Secure .gov websites use HTTPS
A lock ( lock ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.


Search for: All records

Creators/Authors contains: "Singh, Deepak"

Note: When clicking on a Digital Object Identifier (DOI) number, you will be taken to an external site maintained by the publisher. Some full text articles may not yet be available without a charge during the embargo (administrative interval).
What is a DOI Number?

Some links on this page may take you to non-federal websites. Their policies may differ from this site.

  1. null (Ed.)
  2. Abstract. The Snow, Ice, and Aerosol Radiative (SNICAR) model has been used in various capacities over the last 15 years to model the spectral albedo of snow with light-absorbing constituents (LACs). Recent studies have extended the model to include an adding-doubling two-stream solver and representations of non-spherical ice particles; carbon dioxide snow; snow algae; and new types of mineral dust, volcanic ash, and brown carbon. New options also exist for ice refractive indices and solar-zenith-angle-dependent surface spectral irradiances used to derive broadband albedo. The model spectral range was also extended deeper into the ultraviolet for studies of extraterrestrial and high-altitude cryospheric surfaces. Until now, however, these improvements and capabilities have not been merged into a unified code base. Here, we document the formulation and evaluation of the publicly available SNICAR-ADv3 source code, web-based model, and accompanying library of constituent optical properties. The use of non-spherical ice grains, which scatter less strongly into the forward direction, reduces the simulated albedo perturbations from LACs by ∼9 %–31 %, depending on which of the three available non-spherical shapes are applied. The model compares very well against measurements of snow albedo from seven studies, though key properties affecting snow albedo are not fully constrained with measurements, including ice effective grain size of the top sub-millimeter of the snowpack, mixing state of LACs with respect to ice grains, and site-specific LAC optical properties. The new default ice refractive indices produce extremely high pure snow albedo (>0.99) in the blue and ultraviolet part of the spectrum, with such values only measured in Antarctica so far. More work is needed particularly in the representation of snow algae, including experimental verification of how different pigment expressions and algal cell concentrations affect snow albedo. Representations and measurements of the influence of liquid water on spectral snow albedo are also needed. 
    more » « less
  3. null (Ed.)
    Cell cycle is a cellular process that is subject to stringent control. In contrast to the wealth of knowledge of proteins controlling the cell cycle, very little is known about the molecular role of lncRNAs (long noncoding RNAs) in cell-cycle progression. By performing genome-wide transcriptome analyses in cell-cycle-synchronized cells, we observed cell-cycle phase-specific induction of >2000 lncRNAs. Further, we demonstrate that an S-phase-upregulated lncRNA, SUNO1 , facilitates cell-cycle progression by promoting YAP1-mediated gene expression. SUNO1 facilitates the cell-cycle-specific transcription of WTIP , a positive regulator of YAP1, by promoting the co-activator, DDX5-mediated stabilization of RNA polymerase II on chromatin. Finally, elevated SUNO1 levels are associated with poor cancer prognosis and tumorigenicity, implying its pro-survival role. Thus, we demonstrate the role of a S-phase up-regulated lncRNA in cell-cycle progression via modulating the expression of genes controlling cell proliferation. 
    more » « less