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As part of the PI's outreach, a course-based undergraduate research experience engaged undergraduate women in research from examining the literature to identify a gap, formulating a research hypothesis, designing experiments to test the hypothesis, analyzing the data, writing and submitting an abstract and presenting the research to the scientific community. This project was as follows: in the US, 5 million people require blood transfusions each year. Although generally safe, there are drawbacks to blood transfusions including fever, acute immune or delayed hemolytic reactions, anaphylactic reactions, transfusion related acute lung injury, and bloodborne infections. Despite screening for diseases such as HIV and hepatitis, the risk of contraction is nonzero, and there are continually emerging bloodborne diseases such as Zika that are not yet screened for. Additionally, there are often blood bank shortages. These complications have driven decades of research into artificial blood, yet to date there are no blood substitutes clinically available. While hemoglobin based oxygen carriers have shown promise, they also show oxidative damage to tissues, particularly in cardiac and renal tissues. Both high and low oxygen PEGylated hemoglobin (Hb) have shown such oxidative stress. We hypothesized that this oxidative stress was due to direct delivery of the PEGylated Hb and conjugated PEGylated Hb onto PEG hydrogel microspheres. In this study, we probed the ability of the Hb microspheres to deliver oxygen. 

A high frequency solid-state transformer (SST) proposed by FREEDM centre is an interesting alternative to conventional distribution transformer in microgrids as it supports additional functionalities such as active-reactive power flow control, fault current limitation and voltage regulation. This paper proposes a dynamic phasor based robust control of SST through the modular control of each stage. The control problem is formulated in frequency domain by representing the system states with time varying Fourier coefficients or dynamic phasors (DP). This formulation transforms the oscillating waveforms of ac circuits to constant or slowly varying variables, hence allow the use of PI controller to track the sinusoidal references. For rectifier and inverter stages of SST, dq transformation is applied on DP which facilitates the design of PI controller to smoothen out the ripples in the output voltage waveform. The controller gains are tuned to reject input and load disturbances and attenuate measurement noise using loop shaping and pole assignment technique. The robustness of the controller is assured analytically against parametric uncertainties using small gain theorem. Simulation results are provided to support the proposed control scheme. Hardwarein- Loop (HIL) simulation is carried out on critical stages using Opal-RT and dSPACE simulators to confirm the effectiveness of the proposed scheme. 

Abstract Rotating nonaxisymmetric neutron stars (NSs) are promising sources for continuous gravitational waves (CWs). CWs may, if detected, inform us about the internal structure and equation of state of NSs. Here, we present a narrowband search for CWs from known pulsars, for which a matched-filter search can be applied. Narrowband searches are robust to mismatches between electromagnetic (EM) and gravitational emissions, in contrast to fully targeted searches where they are assumed to be phase-locked. In this work, we search for the CW counterparts emitted by 34 pulsars using data from the first and second parts of the fourth LIGO–Virgo–KAGRA observing run. We use the 5n-vector narrowband pipeline, which applies frequency-domain matched filtering. In previous searches, it covered a narrow range in the frequency—frequency time derivative (f— $\dot{f}$) space. Here, we also explore a range in the second time derivative of the frequency $\ddot{f}$around the EM observations. Additionally, for the first time, we target sources in a binary system with this kind of search. We find no evidence for CWs and therefore set upper limits on the strain amplitude emitted by each pulsar. For 20 analyses, we report an upper limit below the theoretical spin-down limit. The tightest constraint is for pulsar PSR J0534+2200 (the Crab pulsar), for which our strain upper limit on the CW amplitude corresponds to ≤0.04% of the spin-down power being radiated in the CW channel. 

Abstract We detail the population properties of binary neutron star, neutron star–black hole binary, and binary black hole mergers using 158 events from the cumulative Gravitational-Wave Transient Catalog 4.0. The black hole primary mass distribution consists of a power-law-like continuum that steepens above 35M_⊙with overdensities at 10M_⊙and 35M_⊙. Binary black holes with primary masses near 10M_⊙are more likely to have less massive secondaries, with a mass ratio distribution peaking at $q=0.71_{-0.11}^{+0.12}$, potentially a signature of stable mass transfer during binary evolution. Black hole spins are inferred to be nonextremal, with 90% of black holes havingχ < 0.6, and preferentially aligned with binary orbits, implying many merging binaries form in isolation. However, we find that a significant fraction, 0.23–0.41, of binaries have negative effective inspiral spins, suggesting many could be formed dynamically in gas-free environments. We find evidence for correlation between effective inspiral spin and mass ratio, driven either by variation in the mode of the distribution or the width. The binary black hole merger rate increases with redshift, consistent with the cosmic star formation density. While there is no evidence of the mass spectrum evolving with redshift, the distribution of effective inspiral spin is found to broaden as redshift increases out toz ≈ 1. We infer the local merger rates (atz= 0) to be 8.8–250 Gpc⁻³yr⁻¹for binary neutron stars, 9.3–86 Gpc⁻³yr⁻¹for neutron star–black hole binaries, and 13–26 Gpc⁻³yr⁻¹for binary black holes; all values reflect central 90% credible intervals.