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Wang X; Dervishi L; Li W; Jiang X; Ayday E; Vaidya J (, AMIA Jt Summits Transl Sci Proc 2023)Kinship relationship estimation plays a significant role in today's genome studies. Since genetic data are mostly stored and protected in different silos, retrieving the desirable kinship relationships across federated data warehouses is a non-trivial problem. The ability to identify and connect related individuals is important for both research and clinical applications. In this work, we propose a new privacy-preserving kinship relationship estimation framework: Incremental Update Kinship Identification (INK). The proposed framework includes three key components that allow us to control the balance between privacy and accuracy (of kinship estimation): an incremental process coupled with the use of auxiliary information and informative scores. Our empirical evaluation shows that INK can achieve higher kinship identification correctness while exposing fewer genetic markers.more » « less
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Wang X.; Dervishi L; Li W.; Jiang X.; Ayday E.; Vaidya J. (, American Medical Informatics Association (AMIA) Annual Symposium)
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Dervishi, L; Wang X.; W. Li, Halimi A.; Vaidya J.; Jiang X.; Ayday E. (, American Medical Informatics Association (AMIA) Annual Symposium)
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