skip to main content
US FlagAn official website of the United States government
dot gov icon
Official websites use .gov
A .gov website belongs to an official government organization in the United States.
https lock icon
Secure .gov websites use HTTPS
A lock ( lock ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.


Search for: All records

Creators/Authors contains: "Yang, Grant"

Note: When clicking on a Digital Object Identifier (DOI) number, you will be taken to an external site maintained by the publisher. Some full text articles may not yet be available without a charge during the embargo (administrative interval).
What is a DOI Number?

Some links on this page may take you to non-federal websites. Their policies may differ from this site.

  1. Understanding the spread of a virus through a large population has always been important for mitigation, treatment, and prevention purposes. In the unprecedented wake of the COVID-19 (SARS-CoV-2) pandemic, techniques to understand and test preventative measures—like vaccination and quarantining—have become increasingly necessary. The developed compartmental model simulates the interactions between (N) people, with variable infection rates for vaccinated (alpha = 0.05) and unvaccinated (Beta = 0.25) people, as well as a (t = 15) day recovery from infection. Both the range of their infectivity, controlled by the quarantine variable (q), and the vaccination rate (f) of the population were varied. The main tests were on the variables of vaccine distribution and effectiveness, as well as quarantine range and the combination between the two. The results suggest that vaccination has a negative linear effect on infection cases over the course of the simulation, while quarantine has a minimal effect until higher amounts (over 80% quarantine), with the inverse being true for duration (increasing with stricter measures). Vaccination and quarantining also have a negative linear and exponential effect respectively on peak case count, which would be helpful in managing the patient flow into hospitals. Reproduction number was also found to be limited below 1.0 by vaccination measures, bringing the outbreak to an end. From these findings, it would be reasonable to suggest that vaccination is nearly ubiquitously helpful, while much stricter quarantine restrictions must be put in place for substantial effect, with the goal to flatten peak cases and decrease reproduction number. 
    more » « less