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  1. Several attacks have been proposed against autonomous vehicles and their subsystems that are powered by machine learning (ML). Road sign recognition models are especially heavily tested under various adversarial ML attack settings, and they have proven to be vulnerable. Despite the increasing research on adversarial ML attacks against road sign recognition models, there is little to no focus on defending against these attacks. In this paper, we propose the first defense method specifically designed for autonomous vehicles to detect adversarial ML attacks targeting road sign recognition models, which is called ViLAS (Vision-Language Model for Adversarial Traffic Sign Detection). The proposed defense method is based on a custom, fast, lightweight, and salable vision-language model (VLM) and is compatible with any existing traffic sign recognition system. Thanks to the orthogonal information coming from the class label text data through the language model, ViLAS leverages image context in addition to visual data for highly effective attack detection performance. In our extensive experiments, we show that our method consistently detects various attacks against different target models with high true positive rates while satisfying very low false positive rates. When tested against four state-of-the-art attacks targeting four popular action recognition models, our proposed detector achieves an average AUC of 0.94. This result achieves a 25.3% improvement over a state-of-the-art defense method proposed for generic image attack detection, which attains an average AUC of 0.75. We also show that our custom VLM is more suitable for an autonomous vehicle compared to the popular off-the-shelf VLM and CLIP in terms of speed (4.4 vs. 9.3 milliseconds), space complexity (0.36 vs. 1.6 GB), and performance (0.94 vs. 0.43 average AUC).

     
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    Free, publicly-accessible full text available June 1, 2025
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  4. The advancements in data acquisition, storage, and processing techniques have resulted in the rapid growth of heterogeneous medical data. Integrating radiological scans, histopathology images, and molecular information with clinical data is essential for developing a holistic understanding of the disease and optimizing treatment. The need for integrating data from multiple sources is further pronounced in complex diseases such as cancer for enabling precision medicine and personalized treatments. This work proposes Multimodal Integration of Oncology Data System (MINDS)—a flexible, scalable, and cost-effective metadata framework for efficiently fusing disparate data from public sources such as the Cancer Research Data Commons (CRDC) into an interconnected, patient-centric framework. MINDS consolidates over 41,000 cases from across repositories while achieving a high compression ratio relative to the 3.78 PB source data size. It offers sub-5-s query response times for interactive exploration. MINDS offers an interface for exploring relationships across data types and building cohorts for developing large-scale multimodal machine learning models. By harmonizing multimodal data, MINDS aims to potentially empower researchers with greater analytical ability to uncover diagnostic and prognostic insights and enable evidence-based personalized care. MINDS tracks granular end-to-end data provenance, ensuring reproducibility and transparency. The cloud-native architecture of MINDS can handle exponential data growth in a secure, cost-optimized manner while ensuring substantial storage optimization, replication avoidance, and dynamic access capabilities. Auto-scaling, access controls, and other mechanisms guarantee pipelines’ scalability and security. MINDS overcomes the limitations of existing biomedical data silos via an interoperable metadata-driven approach that represents a pivotal step toward the future of oncology data integration.

     
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    Free, publicly-accessible full text available March 1, 2025
  5. Free, publicly-accessible full text available January 1, 2025
  6. In this paper, we address the problem of detecting and learning anomalies in high-dimensional data-streams in real-time. Following a data-driven approach, we propose an online and multivariate anomaly detection method that is suitable for the timely and accurate detection of anomalies. We propose our method for both semi-supervised and supervised settings. By combining the semi-supervised and supervised algorithms, we present a self-supervised online learning algorithm in which the semi-supervised algorithm trains the supervised algorithm to improve its detection performance over time. The methods are comprehensively analyzed in terms of computational complexity, asymptotic optimality, and false alarm rate. The performances of the proposed algorithms are also evaluated using real-world cybersecurity datasets, that show a significant improvement over the state-of-the-art results. 
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