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Machine learning (ML) models are successful with weather forecasting and have shown progress in climate simulations, yet leveraging them for useful climate predictions needs exploration. Here we show this feasibility using neural general circulation model (NeuralGCM), a hybrid ML-physics atmospheric model developed by Google, for seasonal predictions of large-scale atmospheric variability and Northern Hemisphere tropical cyclone (TC) activity. Inspired by physical model studies, we simplify boundary conditions, assuming sea surface temperature and sea ice follow their climatological cycle but persist anomalies present at the initialization time. With such forcings, NeuralGCM can generate 100 simulation days in ∼8 min with a single graphics processing unit while simulating realistic atmospheric circulation and TC climatology patterns. This configuration yields useful seasonal predictions (July–November) for the tropical atmosphere and various TC activity metrics. Notably, the predicted and observed TC frequency in the North Atlantic and East Pacific basins are significantly correlated during 1990–2023 (r= ∼0.7), suggesting prediction skill comparable to existing physical GCMs. Despite challenges associated with model resolution and simplified boundary forcings, the model-predicted interannual variations demonstrate significant correlations with the observed sub-basin TC tracks (p< 0.1) and basin-wide accumulated cyclone energy (ACE) (p< 0.01) of the North Atlantic and North Pacific basins. These findings highlight the promise of leveraging ML models with physical insights to model TC risks and deliver seamless weather-climate predictions. 

Projecting climate change is a generalization problem: We extrapolate the recent past using physical models across past, present, and future climates. Current climate models require representations of processes that occur at scales smaller than model grid size, which have been the main source of model projection uncertainty. Recent machine learning (ML) algorithms hold promise to improve such process representations but tend to extrapolate poorly to climate regimes that they were not trained on. To get the best of the physical and statistical worlds, we propose a framework, termed “climate-invariant” ML, incorporating knowledge of climate processes into ML algorithms, and show that it can maintain high offline accuracy across a wide range of climate conditions and configurations in three distinct atmospheric models. Our results suggest that explicitly incorporating physical knowledge into data-driven models of Earth system processes can improve their consistency, data efficiency, and generalizability across climate regimes.