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Photometric redshifts will be a key data product for the Rubin Observatory Legacy Survey of Space and Time (LSST) as well as for future ground and space-based surveys. The need for photometric redshifts, or photo-zs, arises from sparse spectroscopic coverage of observed galaxies. LSST is expected to observe billions of objects, making it crucial to have a photo-z estimator that is accurate and efficient. To that end, we present DeepDISC photo-z, a photo-z estimator that is an extension of the DeepDISC framework. The base DeepDISC network simultaneously detects, segments, and classifies objects in multi-band coadded images. We introduce photo-z capabilities to DeepDISC by adding a redshift estimation Region of Interest head, which produces a photo-z probability distribution function for each detected object. On simulated LSST images, DeepDISC photo-z outperforms traditional catalog-based estimators, in both point estimate and probabilistic metrics. We validate DeepDISC by examining dependencies on systematics including galactic extinction, blending and PSF effects. We also examine the impact of the data quality and the size of the training set and model. We find that the biggest factor in DeepDISC photo-z quality is the signal-to-noise of the imaging data, and see a reduction in photo-z scatter approximately proportional to the image data signal-to-noise. Our code is fully public and integrated in the RAIL photo-z package for ease of use and comparison to other codes at https://github.com/LSSTDESC/rail_deepdisc 

ABSTRACT We present posterior sample redshift distributions for the Hyper Suprime-Cam Subaru Strategic Program Weak Lensing three-year (HSC Y3) analysis. Using the galaxies’ photometry and spatial cross-correlations, we conduct a combined Bayesian Hierarchical Inference of the sample redshift distributions. The spatial cross-correlations are derived using a subsample of Luminous Red Galaxies (LRGs) with accurate redshift information available up to a photometric redshift of z < 1.2. We derive the photometry-based constraints using a combination of two empirical techniques calibrated on spectroscopic and multiband photometric data that cover a spatial subset of the shear catalogue. The limited spatial coverage induces a cosmic variance error budget that we include in the inference. Our cross-correlation analysis models the photometric redshift error of the LRGs to correct for systematic biases and statistical uncertainties. We demonstrate consistency between the sample redshift distributions derived using the spatial cross-correlations, the photometry, and the posterior of the combined analysis. Based on this assessment, we recommend conservative priors for sample redshift distributions of tomographic bins used in the three-year cosmological Weak Lensing analyses. 

ABSTRACT Recovering credible cosmological parameter constraints in a weak lensing shear analysis requires an accurate model that can be used to marginalize over nuisance parameters describing potential sources of systematic uncertainty, such as the uncertainties on the sample redshift distribution n(z). Due to the challenge of running Markov chain Monte Carlo (MCMC) in the high-dimensional parameter spaces in which the n(z) uncertainties may be parametrized, it is common practice to simplify the n(z) parametrization or combine MCMC chains that each have a fixed n(z) resampled from the n(z) uncertainties. In this work, we propose a statistically principled Bayesian resampling approach for marginalizing over the n(z) uncertainty using multiple MCMC chains. We self-consistently compare the new method to existing ones from the literature in the context of a forecasted cosmic shear analysis for the HSC three-year shape catalogue, and find that these methods recover statistically consistent error bars for the cosmological parameter constraints for predicted HSC three-year analysis, implying that using the most computationally efficient of the approaches is appropriate. However, we find that for data sets with the constraining power of the full HSC survey data set (and, by implication, those upcoming surveys with even tighter constraints), the choice of method for marginalizing over n(z) uncertainty among the several methods from the literature may modify the 1σ uncertainties on Ωm–S8 constraints by ∼4 per cent, and a careful model selection is needed to ensure credible parameter intervals. 

Abstract Branched DNA motifs serve as the basic construction elements for all synthetic DNA nanostructures. However, precise control of branching orientation remains a key challenge to further heighten the overall structural order. In this study, we use two strategies to control the branching orientation. The first one is based on immobile Holliday junctions which employ specific nucleotide sequences at the branch points which dictate their orientation. The second strategy is to use angle‐enforcing struts to fix the branching orientation with flexible spacers at the branch points. We have also demonstrated that the branching orientation control can be achieved dynamically, either by canonical Watson–Crick base pairing or non‐canonical nucleobase interactions (e.g., i‐motif and G‐quadruplex). With precise angle control and feedback from the chemical environment, these results will enable novel DNA nanomechanical sensing devices, and precisely‐ordered three‐dimensional architectures.